Maria Isabel Rodriguez

• María Isabel Rodríguez (government official), former Minister of Health of El Salvador ; former Rector of the University of El Salvador
• Misa Rodríguez, Spanish football goalkeeper
• María Isabel, winner of the Junior Eurovision Song Contest 2004
• María Isabel Rodríguez Lineros, known as Lucía, represented Spain in the 1982 Eurovision Song Contest
• Maria Isabel Rodriguez, co-author of two novels with André Launay