Maragatham Chandrasekhar was born Maragatham Muniswami to Vidwan Kalathur Muniswami on 11 November 1917. She obtained her Bachelor of Science degree in India and completed diplomas in free-lance, domestic science and dietetics courses in London. She also did a course on Specialized Institution Management and Administration at London. Maragatham married R. Chandrasekhar and had a son and a daughter, Lata Priyakumar who also served as a Member of the Legislative Assembly of Tamil Nadu.