Manuel Aguirre
Manuel Aguirre may refer to:
- Manuel Aguirre, 20th-century Mexican general and leader of the Escobarista rebellion
- Manuel Aguirre de Tejada, Spanish politician
- Manuel Aguirre Geisse, Minister of Health of Chile for three weeks in February 1950
- Manuel Aguirre y Monsalbe, Spanish painter
- Manuel Aguirre (rugby union), Argentine rugby union player
- Manuel Bernardo Aguirre, Mexican politician
- Manuel Aguirre, a character in Rebelde Way, an Argentine telenovela
- Manuel Aguirre, a Jesuit missionary to New Spain