Mantle zone

The mantle zone of a lymphatic nodule is an outer ring of small lymphocytes surrounding a germinal center.
It is also known as the "corona".
It contains transient lymphocytes.
It is the location of the lymphoma in mantle [cell lymphoma].

Pathology

Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e., Mantle cell lymphoma. Tcl-1 is expressed in the mantle zone.