Mantle zone
The mantle zone of a lymphatic nodule is an outer ring of small lymphocytes surrounding a germinal center.
It is also known as the "corona".
It contains transient lymphocytes.
It is the location of the lymphoma in mantle cell lymphoma.
Pathology
Image:Castleman disease - intermed mag.jpg|thumb|right|Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stainMantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e., Mantle cell lymphoma. Tcl-1 is expressed in the mantle zone.