M. angustisecta is native to arid and semiarid deserts of Peru. It has been identified in the Arequipa and Caravelí Provinces, Province Mariscal Nieto, and Tarata and Candarave provinces. It can be found at altitudes of 1800-3035m.
Conservation status
Malesherbia angustisecta is currently considered endangered due to its restricted distribution.