MTL
- CF Montréal
- First language
- Japan Median Tectonic Line
- MTL (transport company)
- MTL Harbor Tugboats
- MTL Instruments Group
- Machine translation
- Maitland Airport
- Maltese lira
- Marc Tessier-Lavigne
- Mary Todd Lincoln
- Massachusetts Institute of Technology
- Master of Teaching and Learning
- Material Template Library
- Materials Technology Laboratory
- Matrix Template Library
- Merged transistor logic
- Meteor Lake
- Metric temporal logic
- Model transformation language
- Modern Terminals Limited
- Monoidal t-norm logic
- Montreal
- Montreal Alouettes
- Montreal Canadiens
- Mortlake railway station
- Mount Laurel Township, New Jersey
- Muldentalkreis
- Multi-task learning
- RAF-Avia