MTD
- Champaign–Urbana Mass Transit District
- MTD (mobile network)
- MTD Products
- MTD(f)
- Making Tax Digital
- Makkal Tamil Desam Katchi
- Maximum tolerated dose
- Memory technology device
- Metadynamics
- Metal Trades Department of the AFL-CIO
- Michael Tobias Design
- Month-To-Date
- Moralistic therapeutic deism
- Movimiento de Trabajadores Desempleados
- Muscle tension dysphonia