MSF
- List of characters in the Metal Gear series
- List of mine warfare vessels of the United States Navy
- Manufacturing, Science and Finance
- Master of Science in Finance
- Mathematical Sciences Foundation
- Methanesulfonyl fluoride
- Microsoft Solutions Framework
- Military science fiction
- Mind Science Foundation
- Ministry of Social and Family Development
- Misfits Gaming
- Mork (file format)
- Motorcycle Safety Foundation
- Multi-Stage Flash
- Multiple streams framework
- Multiservice Switching Forum
- Mundane science fiction
- Muslim Safety Forum
- Médecins Sans Frontières
- Socialist Appeal (UK, 1992)
- Time from NPL