MSE
- 17th Signal Battalion (United States)
- Canada–France–Hawaii Telescope
- Information and Communications University
- Kent International Airport
- MSE (centrifuges)
- Macedonian Stock Exchange
- Madras Stock Exchange
- Madrid Stock Exchange
- Malawi Stock Exchange
- Malta Stock Exchange
- Manned Spaceflight Engineer Program
- Mars Surface Exploration
- Martha Stewart Living Omnimedia
- Master of Science in Engineering
- Materials science
- Maunakea Spectroscopic Explorer
- Maximum spacing estimation
- Mean squared error
- Mechanically stabilized earth
- Media Source Extensions
- Medical Science Educator
- Melbourne String Ensemble
- Mental status examination
- Mercury Surface Element
- Message Stream Encryption
- Metasearch engine
- Micro-enterprise
- Microsoft Security Essentials
- Ministry of Sustainability and the Environment
- Mississippi Export Railroad
- Mobile Subscriber Equipment
- MoneySavingExpert.com
- Mongolian Stock Exchange
- Montenegro Stock Exchange
- Montreal Stock Exchange
- Odakyu 60000 series MSE
- Selenomethionine
- Small business