MPE
- .MPE
- Griswold Airport
- HP Multi-Programming Executive
- Laser safety
- MIDI
- MIDI Polyphonic Expression
- Madison, Connecticut
- Malignant pleural effusion
- Markov perfect equilibrium
- Max Planck Institute for Extraterrestrial Physics
- Mean percentage error
- Media processing engine
- Methidiumpropyl-EDTA
- Minimum polynomial extrapolation
- Miss Philippines Earth
- Molecular pathological epidemiology
- Mors Principium Est
- Multiprotocol Encapsulation
- Mumbai–Pune Expressway
- Myxopapillary ependymoma
- Phaswane Mpe
- Philadelphia Municipal Airport