2-Hydroxy-3-morpholinopropanesulfonic acid
MOPSO is a zwitterionic organic chemical buffering agent; one of Good's buffers. MOPSO and MOPS are chemically similar, differing only in the presence of a hydroxyl group on the C-2 of the propane moiety. It has a useful pH range of 6.5-7.9 in the physiological range, making it useful for cell culture work. It has a pKa of 6.9 with ΔpKa/°C of -0.015 and a solubility in water at 0°C of 0.75 M.
MOPSO has been used as a buffer component for:
- Copper analysis via:
- * Flow injection micellar technique of the catalytic reaction of 3-methyl-2-benzothiazolinone hydrazone and N-ethyl-N--3,5-dimethoxyaniline
- * Electrospray ionization quadrupole time-of-flight mass spectroscopy to measure MOPSO-copper chelated complexes
- Discontinuous gel electrophoresis on rehydratable polyacrylamide gels
- Buffered charcoal yeast extract agar
- Fixing cells in urine in a buffered alcohol
- Testing crude oil bioremediation products in marine environments