MGS-0039

MGS-0039 is a drug that is used in neuroscientific research, which acts as a potent and selective antagonist for Metabotropic [glutamate receptor#Group II and Group III|group II] of the metabotropic glutamate receptors. It produces antidepressant and anxiolytic effects in animal studies, and has been shown to boost release of dopamine and serotonin in specific brain areas. Research has suggested this may occur through a similar mechanism as that suggested for the similarly glutamatergic drug ketamine.