Lysergic acid tert-butylamide
Lysergic acid tert-butylamide, also known as N-''tert''-butyllysergamide, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide. It was described in an early patent as reportedly being psychoactive and hallucinogenic and as producing hypothermia and "anti-hypothalamic" effects presumably in animals. The drug shows activity at serotonin receptors, but is a very low-potency agonist of the serotonin 5-HT2A receptor. The chemical synthesis of LAtB has been described and analytical characterization has been described. It was first described in the literature in a patent by Richard P. Pioch at Eli Lilly and Company in 1961. The drug's pharmacology was later studied by David E. Nichols and colleagues.