Lutidine

Lutidine is the trivial name used to describe the chemical compounds which are dimethyl derivatives of pyridine. They were discovered in Dippel's oil and named by Thomas Anderson in 1851. Their chemical properties resemble those of pyridine, although the presence of the methyl groups may prohibit some of the more straightforward reactions. Lutidine comes in several isomers:

2,3-Lutidine
2,4-Lutidine
2,5-Lutidine
2,6-Lutidine
3,4-Lutidine
3,5-Lutidine

All isomers share the molecular weight 107,16 g/mol and the chemical formula C₇H₉N.

Applications

3,4-Lutidine has formal application in the synthesis of a large bevy of benzomorphan opioid analgesics including: Metazocine, Phenazocine, Ketazocine, Pentazocine, Tonazocine, Volazocine, Cyclazocine, Alazocine, 8-Carboxamidocyclazocine, Fluorophen, Quadazocine, ID-1229, LP-1, MR-2034 .
2,3-Lutidine has application in the synthesis of Rabeprazole, Lansoprazole, Ilaprazole