Lumi-LSD


Lumi-LSD, also known as 10-hydroxy-9,10-dihydro-LSD or as N,''N''-diethyl-9,10-dihydro-10-hydroxylysergamide, is a lysergamide and chemical degradation product of the psychedelic drug lysergic [acid diethylamide]. LSD is converted into lumi-LSD by exposure to light, specifically ultraviolet light. Lumi-LSD might also be a metabolite of LSD, but this remains unconfirmed.

Pharmacology

Pharmacodynamics

Lumi-LSD showed 0.01% of the antiserotonergic activity of LSD in the isolated rat uterus in vitro. As such, lumi-LSD was regarded as essentially inactive in this assay. Similarly, lumi-LSD shows abolished physiological and behavioral effects in animals and is said to be inactive in terms of hallucinogenic effects in humans. Likewise, in contrast to LSD, lumi-LSD was found to be inactive in terms of electroencephalogram changes in rabbits.

Chemistry

Unlike LSD, lumi-LSD is not fluorescent.
Other lumi-lysergamides are also known.

History

Lumi-LSD was first described in the scientific literature by at least 1955.