John Luke
John Luke may refer to:
- John A. Luke Jr., chief executive officer of MeadWestvaco
- John Luke (artist), Irish artist
- John Luke (died 1452), MP for Dunwich (UK [Parliament constituency)]
- John Luke (English politician), English politician who sat in the House of Commons from 1610 to 1611
- John Luke (New Zealand politician), New Zealand politician
- John-Luke Roberts, British stand-up comedian, writer, actor and performer