Long-range action of Nodal requires interaction with GDF1
Long-range action of Nodal requires interaction with GDF1 is a scholarly work by Hiroshi Hamada, published in 2007 in ''Genes & Development''. The main subjects of the publication include embryo, Nodal signaling, Nodal growth differentiation factor, anatomy, biology, Notch signaling pathway, TGF beta signaling pathway, cell biology, and development of the heart. In contrast to previous observations, authors now show that GDF1 itself is not an effective ligand but rather functions as a coligand for Nodal.