List of protein secondary structure prediction programs
List of notable protein secondary structure prediction programs
| Name | Method description | Type | Link | Initial release |
| RaptorX-SS8 | predict both 3-state and 8-state secondary structure using conditional neural fields from PSI-BLAST profiles | Webserver/downloadable | 2011 | |
| GOR | Information theory/Bayesian inference | Many implementations | 2002 | |
| Jpred | Multiple Neural network assignment from PSI-BLAST and HMMER profiles. Predicts secondary structure and solvent accessibility | Webserver | 1998 | |
| PredictProtein | Profile-based neural network | Webserver | 1992 | |
| PSIPRED | two feed-forward neural networks which perform an analysis on output obtained from PSI-BLAST | Webserver | 1999 |