List of largest cities in the Americas
This is a list of the 50 largest cities in the Americas by population residing within city limits based on the most recent official census results, estimates, or short-term projections available for all of these cities, which refer to mid-2020 populations. These figures do not reflect the population of the urban agglomeration or metropolitan area which typically do not coincide with the administrative boundaries of the city. For a list of the latter, see List of metropolitan areas in the Americas by population. These figures refer to mid-2020 populations with the following exceptions:
- Mexican cities, whose figures derive from the 2015 Intercensal Survey conducted by INEGI with a reference date of March 15, 2020;
- Chilean cities, whose figures derive from the 2017 Census projection by Instituto Nacional de Estadísticas;
- Venezuelan cities, whose figures originate from the 2015 estimate given by the Instituto Nacional de Estadística, with a reference date of 2016.
| City | Image | Country | Population | Year | |
| 1 | São Paulo | 11,904,961 | 2025 | ||
| 2 | Lima | 10,092,000 | 2023 | ||
| 3 | Mexico City | refn|Population estimate is that of the federal entity known since 2016 as Ciudad de México and previously as the Distrito Federal.|group=lower-alphaUSACOLrefn|Population projections for Colombian cities are that of the cabecera municipal.|name=Colombia|group=lower-alphaBRACHLUSAVENrefn|Population projection is that of the Metropolitan District of Caracas, which comprises the municipalities of Libertador, Chacao, Baruta, Sucre and El Hatillo.|group=lower-alphaARG |
refn|Population estimate is that of the