| Podcast | Year | Starring, Narrator, or Host | Produced by | Ref |
| 372 Pages We'll Never Get Back | 2017–present | Michael J. Nelson and Conor Lastowka | Independent | |
| The Adam Buxton Podcast | 2015–present | Adam Buxton | Independent | |
| The Adam Carolla Show | 2005–present | Adam Carolla, Bryan Bishop, and Gina Grad | PodcastOne | |
| Adulting | 2019 | Michelle Buteau and Jordan Carlos | WNYC Studios | |
| And That's Why We Drink | 2017–present | Christine Schiefer and Em Schulz | Kast Media | |
| Another Round | 2015–2017 | Tracy Clayton and Heben Nigatu | Panoply Media and BuzzFeed | |
| Answer Me This! | 2007–2021; 2023 | Helen Zaltzman and Olly Mann | Independent | |
| The Anthony Cumia Show | | Anthony Cumia | | |
| Armchair Expert | | | | |
| Attitudes! | | | | |
| Emergency Intercom | 2021 –present | Enya Umanzor and Drew Phillips | Tiny Meat Gang | |
| The Baby-Sitters Club Club | | | | |
| The Bald and the Beautiful | | | | |
| Beach too Sandy, Water too Wet | 2018 | siblings Alex and Christine Schiefer | | |
| Beef And Dairy Network Podcast | | | | |
| The Best Show with Tom Scharpling | 2000–2013, 2014–present | Tom Scharpling, Jon Wurster | | |
| Black Men Can't Jump (In Hollywood) | | | | |
| Blank Check with Griffin & David | | | | |
| The Brilliant Idiots | | | | |
| Bubble | | | | |
| The Bugle | | | | |
| Bullseye with Jesse Thorn | | | | |
| Call Her Daddy | | | | |
| Can I Pet Your Dog? | | | | |
| The Champs | | | | |
| Chapo Trap House | | | | |
| Come to Papa | | | | |
| The Comedian's Comedian with Stuart Goldsmith | | | | |
| Comedy Bang! Bang! | 2009–present | Scott Aukerman | Earwolf | |
| Comments by Celebs | | | | |
| The Complete Guide to Everything | | | | |
| Conan O'Brien Needs a Friend | 2018–present | Conan O'Brien, Matt Gourley, and Sona Movsesian | Team Coco and Earwolf | |
| Crime Writers On | | | | |
| Cum Town | 2016-2022 | Nick Mullen, Stavros Halkias, and Adam Friedland | Nick Mullen | |
| The Dead Authors Podcast | | | | |
| Dear Hank & John | | | | |
| Desus vs. Mero | | | | |
| Do the Right Thing | | | | |
| The Dollop | | | | |
| Doogtoons | | | | |
| Dopey | | | | |
| Doug Stanhope's Podcast | | | | |
| Doughboys | | | | |
| The Drew and Mike Podcast | | | | |
| Drunken Peasants | | | | |
| Dudesy | 2022-2024 | Will Sasso and Chad Kultgen | | |
| The Duncan Trussell Family Hour | 2012–present | Duncan Trussell | | |
| Ear Biscuits | 2013–present | Rhett and Link | Audacy, Inc. | |
| Endless Thread | | | | |
| The Flop House | | | | |
| Gay Pimpin' with Jonny McGovern | | | | |
| Get Played | | | | |
| Getting Doug with High | | | | |
| Gilmore Guys | | | | |
| Girl on Guy | | | | |
| The Glass Cannon | | | | |
| Good for You | | | | |
| Good Muslim, Bad Muslim | | | | |
| The Greatest Generation | | | | |
| The Guilty Feminist | | | | |
| Guys We Fucked | | | | |
| Harmontown | 2012-2019 | Dan Harmon and Jeff B. Davis | | |
| Hello from the Magic Tavern | | | | |
| Hello Internet | | | | |
| The Hilarious World of Depression | | | | |
| Hollywood Babble-On | 2010–present | Kevin Smith and Ralph Garman | SModcast Podcast Network | |
| Hollywood Handbook | | | | |
| How Did This Get Made? | | | | |
| How Was Your Week with Julie Klausner | 2011–present | Julie Klausner | Independent | |
| I Seem Fun: The Diary of Jen Kirkman | | | | |
| ID10T with Chris Hardwick | 2010–present | Chris Hardwick, | Cadence13 | |
| If I Were You | | | | |
| International Waters | | | | |
| Jay & Silent Bob Get Old | 2010-2020 | Kevin Smith and Jason Mewes | SModcast Podcast Network | |
| The Joe Rogan Experience | 2009–present | Joe Rogan | Jamie Vernon and Joe Rogan | |
| Jordan, Jesse, Go! | 2007–present | Jordan Morris and Jesse Thorn | Maximum Fun | |
| Judge John Hodgman | 2010–present | John Hodgman and Jesse Thorn | Maximum Fun | |
| Keith and The Girl | | | | |
| Knowledge Fight | | | | |
| Las Culturistas | | | | |
| The Last Podcast on the Left | | | | |
| Le donjon de Naheulbeuk | | | | |
| Leyendas Legendarias | | | | |
| Loveline | | | | |
| Lovett or Leave It | | | | |
| Low Blows | | | | |
| Maintenance Phase | | | | |
| Mega64 | 2006–present | Rocco Botte, Derrick Acosta, and Shawn Chatfield | | |
| The Memory Palace | | | | |
| Midwest Teen Sex Show | | | | |
| The Misfits Podcast | 2018-2022 | Cameron 'Fitz' McKay, Mason 'Zuckles' Bradford, McCreamy, Swaggersouls, Tobi 'TobiOnTheTele' Lyons | | |
| Mission to Zyxx | | | | |
| Monday Morning Podcast | 2007-2012 | Bill Burr | | |
| My Brother, My Brother and Me | | | | |
| My Dad Wrote a Porno | 2015-2022 | Jamie Morton, James Cooper, and Alice Levine | | |
| My Favorite Murder | | | | |
| Nerd Poker | 2012–2015, 2017–present | Brian Posehn, Blaine Capatch, Chris Tallman, Dan Telfer, Ken Daly, Sam Kieffer | Independent | |
| Never Not Funny | | | | |
| The News Quiz | | | | |
| Newsjack | | | | |
| No Agenda | | | | |
| Norm Macdonald Live | 2013-2017 | Norm Macdonald and Adam Eget | Daniel Kellison | |
| The Now Show | | | | |
| Off Menu with Ed Gamble and James Acaster | | | | |
| Office Ladies | 2019–present | Jenna Fischer and Angela Kinsey | Earwolf | |
| OMGWTFBible | | | | |
| On Cinema | | | | |
| The ParaPod | | | | |
| Pardon My Take | 2016-present | Dan "Big Cat" Katz and PFT Commenter | Barstool Sports | |
| The Peacock and Gamble Podcast | | | | |
| Perfect Guy Life | 2021–present | Sam Hyde and Nick Rochefort | Independent | |
| Pod Meets World | | | | |
| Podcast But Outside | | | | |
| Politically Re-Active | | | | |
| Pop My Culture | | | | |
| Potterless | | | | |
| Probably Science | | | | |
| Professor Blastoff | | | | |
| The Read | | | | |
| Red Man Laughing | | | | |
| Red Scare | 2018–present | Dasha Nekrasova and Anna Khachiyan | | |
| Richard Herring's interview podcasts | | | | |
| The Ricky Gervais Show | 2005-2011 | Ricky Gervais, Stephen Merchant, and Karl Pilkington | | |
| RISK! | | | | |
| Ronna and Beverly | | | | |
| Rooster Teeth Podcast | 2008-2024 | Burnie Burns, Geoff Ramsey, Joel Heyman, Gus Sorola | | |
| RuPaul: What's the Tee? | 2014–present | RuPaul and Michelle Visage | | |
| Sawbones | | | | |
| Screen Junkies | | | | |
| Shagged Married Annoyed | | | | |
| Shameless | | | | |
| The Six Pack | | | | |
| SmartLess | | | | |
| SModcast | 2010–present | Kevin Smith and Scott Mosier | SModcast Podcast Network | |
| The Socially Distant Sports Bar | | | | |
| Spittin' Chiclets | | | | |
| Spontaneanation | | | | |
| Star Wars Minute | | | | |
| StarTalk | | | | |
| The Starters | | | | |
| Stephen Fry's Podgrams | | | | |
| Stop Podcasting Yourself | | | | |
| Straight Talk with Ross Mathews | | | | |
| Street Fight Radio | | | | |
| Superego | | | | |
| Surprisingly Awesome | | | | |
| Talk Tuah | | | | |
| Tell 'Em Steve-Dave! | | | | |
| Ten Minute Podcast | 2012-2018 | Will Sasso, Chris D'Elia, and Bryan Callen | | |
| This Sounds Serious | | | | |
| Three Bean Salad | 2021-present | Benjamin Partridge, Mike Wozniak, and Henry Paker | Independent | |
| TOFOP | | | | |
| Tom Rhodes Radio | | | | |
| Too Beautiful to Live | | | | |
| Uhh Yeah Dude | | | | |
| UNHhhh, the Podcast | | | | |
| Unqualified | | | | |
| A Very Fatal Murder | | | | |
| Wait Wait... Don't Tell Me! | | | | |
| Walking the Room | | | | |
| Welcome to Night Vale | | | | |
| Were You Raised By Wolves? | | | | |
| Who? Weekly | | | | |
| Why I'm Not... with Brant Pinvidic | | | | |
| Why Won't You Date Me? | | | | |
| Wikishuffle | | | | |
| With Special Guest Lauren Lapkus | | | | |
| Womp It Up! | | | | |
| Wooden Overcoats | | | | |
| The Worst Idea of All Time | | | | |
| WTF with Marc Maron | 2009–present | Marc Maron | Brendan McDonald | |
| Yeah, But Still | | | | |
| Yo, Is This Racist? | | | | |
| You Made It Weird with Pete Holmes | | | | |
| Your Mom's House | | | | |
| The Carlötta Beautox Chronicles | | | | |