| Territory | Claimants | Notes |
| Guyana west of the Essequibo River and Ankoko Island | '
| Approximately two-thirds of Guyana's sovereign territory is claimed by Venezuela. Following arbitration, a demarcated border was established in 1905 following the Arbitral Award of 1899 but was later contested by Venezuela in 1962 following the publication of the Mallet-Prevost memorandum. The crisis was renewed recently following the discovery of oil deposits. |
| Arroyo de la Invernada or Rincón de Artigas and Vila Albornoz | '
| Dispute in the Invernada River region near Masoller, over which tributary represents the legitimate source of the Quaraí River/Cuareim River. The UN does not officially recognize the claim. |
| Falkland Islands and South Georgia and the South Sandwich Islands | '
| See Falkland Islands sovereignty dispute and South Georgia and the South Sandwich Islands sovereignty dispute. |
| French Guiana and Suriname involving the Maroni River | '
| The source or tributary of the Lawa River between Suriname and French Guiana is disputed but eventually follows to the tripoint with Brazil. The Netherlands, and now Suriname, contends that the boundary follows the Malani River to the east, while France asserts that the border follows the Litani River to the west. |
| New River Triangle (Tigri Area) involving the Courantyne River and the New River | '
| The New River Triangle is a region within the Guiana Highlands that has been disputed by Suriname and Guyana since the 19th century. It involves the Courantyne River and the interpreted source of the river. In 1871, the New River was discovered, questioning the boundary between the two states. |
| Isla Brasilera/Ilha Brasileira | '
| Uruguayan officials claim that the island falls under their Artigas Department. |
| Isla Suárez/Ilha de Guajará-mirim | '
| An island in the river Rio Mamoré that serves as a border between Bolivia and Brazil, alongside the other 80 islands that are not assigned to any country. Isla Suárez is geographically closer to Bolivia, however economically dependent on the Brazilian city of Guajará-Mirim. Both countries signed a treaty in 1958 that keeps the island in a status quo. |
| Southern Patagonian Ice Field |
| From Mount Fitz Roy to Cerro Murallón the border remains undefined, while in the zone of Murallón and Cerro Daudet both countries already defined a border in 1998, but their respective cartographies differ. |
| Isla Santa Rosa | '
| A small island in Amazon River near Colombian city of Leticia. It emerged around 1970, and was administered by Peru since then. In 2025, Colombian government argued that the treaties set the boundary between the two countries at the deepest point of the Amazon River, and that islands like Santa Rosa have emerged on the Colombian side of that dividing line. |