| Rank | Player | Pos | Team played for | Total assists | Games played | Assists per game average |
| 1 | Sue Bird* | G | Seattle Storm | 3,234 | 580 | 5.6 |
| 2 | Courtney Vandersloot^ | G | Chicago Sky New York Liberty | 2,887 | 435 | |
| 3 | Ticha Penicheiro | G | Sacramento Monarchs Los Angeles Sparks Chicago Sky | 2,600 | 454 | 5.7 |
| 4 | Diana Taurasi† | G | Phoenix Mercury | 2,394 | 565 | |
| 5 | Lindsay Whalen* | G | Connecticut Sun Minnesota Lynx | 2,345 | 480 | 4.9 |
| 6 | Chelsea Gray^ | G | Connecticut Sun Los Angeles Sparks Las Vegas Aces | 1,870 | 369 | |
| 7 | Alyssa Thomas^ | F | Connecticut Sun | 1,820 | 358 | |
| 8 | Skylar Diggins^ | G | Tulsa Shock/Dallas Wings Phoenix Mercury Seattle Storm | 1,768 | 335 | |
| 9 | Natasha Cloud^ | G | Washington Mystics Phoenix Mercury | 1,733 | 327 | |
| 10 | Becky Hammon* | G | New York Liberty San Antonio Silver Stars/San Antonio Stars | 1,708 | 450 | 3.8 |
| 11 | Candace Parker† | F/C | Los Angeles Sparks Chicago Sky Las Vegas Aces | 1,634 | 410 | 4.0 |
| 12 | Cappie Pondexter | G | Phoenix Mercury New York Liberty Chicago Sky Los Angeles Sparks Indiana Fever | 1,578 | 416 | 3.8 |
| 13 | Tamika Catchings* | F | Indiana Fever | 1,488 | 457 | 3.3 |
| 14 | Danielle Robinson† | G | San Antonio Silver Stars/San Antonio Stars/Las Vegas Aces Phoenix Mercury Minnesota Lynx Indiana Fever Atlanta Dream | 1,479 | 359 | |
| 15 | Shannon Johnson | G | Orlando Miracle/Connecticut Sun San Antonio Silver Stars Detroit Shock Houston Comets Seattle Storm | 1,424 | 352 | 4.0 |
| 16 | Tanisha Wright | G | Seattle Storm New York Liberty Minnesota Lynx | 1,422 | 457 | 3.1 |
| 17 | Temeka Johnson | G | Washington Mystics Los Angeles Sparks Phoenix Mercury Tulsa Shock Seattle Storm | 1,382 | 327 | 4.2 |
| 18 | Courtney Williams^ | G | Phoenix Mercury Connecticut Sun Atlanta Dream Chicago Sky Minnesota Lynx | 1,365 | 333 | |
| 19 | Jasmine Thomas† | G | Washington Mystics Atlanta Dream Connecticut Sun Los Angeles Sparks | 1,356 | 390 | 3.5 |
| 20 | Briann January | G | Indiana Fever Phoenix Mercury Connecticut Sun Seattle Storm | 1,339 | 393 | 3.4 |
| 21 | Teresa Weatherspoon* | G | New York Liberty Los Angeles Sparks | 1,338 | 254 | 5.3 |
| 22 | Dawn Staley* | G | Charlotte Sting Houston Comets | 1,337 | 263 | 5.1 |
| 23 | Kristi Toliver† | G | Chicago Sky Los Angeles Sparks Washington Mystics | 1,300 | 380 | |
| 24 | Katie Smith* | G/F | Minnesota Lynx Detroit Shock Washington Mystics Seattle Storm New York Liberty | 1,258 | 482 | 2.6 |
| 25 | Erica Wheeler^ | G | Atlanta Dream New York Liberty Indiana Fever Los Angeles Sparks Seattle Storm | 1,256 | 341 | |