| Number of workers | Strike | Date | Place |
| 4,300,000–5,000,000 | Strike wave of 1945–46 | 1945–46 | nationwide |
| 4,000,000 | Strike wave of 1919 | 1919 | nationwide |
| 750,000–800,000 | 1946 Steel Strike | 1946 | nationwide |
| 675,000 | 1983 AT&T strike | 1983 | nationwide |
| 610,000 | 1922 UMW General coal strike | 1922 | nationwide |
| 560,000 | 1952 steel strike | 1952 | nationwide |
| 540,000 | 1971 Rail strike | 1971 | nationwide |
| 519,000 | Steel strike of 1959 | 1959 | nationwide |
| 500,000 | 1956 steel strike | 1956 | nationwide |
| 500,000 | 1949 steel strike | 1949 | naionwide |
| 459,000 | 1967 US Railroad strike | 1967 | nationwide |
| 440,000 | 1971 Telephone strike | 1971 | nationwide |
| 400,000 | 1970 General Motors Strike | 1970 | nationwide |
| 400,000 | Textile workers' strike (1934) | 1934 | New England, Mid-Atlantic region and U.S. southern states |
| 400,000 | Great Railroad Strike of 1922 | 1922 | nationwide |
| 400,000 | 1955 Steel strike | 1955 | nationwide |
| 400,000 | 1949 US coal strike | 1949 | nationwide |
| 400,000 | 1946 UMW mine strike | 1946 | nationwide |
| 400,000 | 1935 US Bituminous Coal Strike | 1935 | nationwide |
| 394,000 | 1919 UMW Coal strike | 1919 | nationwide |
| 370,000 | Telephone Strike | 1947 | nationwide |
| 365,000 | Steel strike of 1919 | 1919 | nationwide |
| 360,000 | 1943 Bituminous coal strike | 1943 | nationwide |
| 343,000 | 1947 Bituminous coal strike | 1947 | nationwide |
| 330,000 | 1939 US Bituminous coal strike | 1939 | nationwide |
| 321,000 | 1978 Railroad strike | 1978 | nationwide |
| 320,000 | United Auto Workers strike of 1945–1946 | 1945 | nationwide |
| 320,000 | 1948 US Bituminous coal strike | 1948 | nationwide |
| 300,000 | 1958 General Motors strike | 1958 | nationwide |
| 275,000 | 1964 General Motors strike | 1964 | nationwide |
| 270,000 | 1952 Bituminous coal strike | 1952 | nationwide |
| 257,000 | 1969 Telephone strike | 1969 | nationwide |
| 250,000 | Pullman Strike | 1894 | Originally Pullman, Chicago, spread nationwide |
| 250,000 | 1946 Rail Strike | 1946 | nationwide |
| 249,300 | 1976 Truckers strike | 1976 | nationwide |
| 239,000 | 1961 General Motors Strike | 1961 | nationwide |
| 219,400 | 1979 Truckers strike | 1979 | nationwide |
| +205,207 | Bituminous coal miners' strike | 1894 | nationwide |
| +200,000 | Great Southwest railroad strike | 1886 | nationwide |
| 200,000 | U.S. Postal Service strike of 1970 | 1970 | nationwide |
| 200,000 | 1927 Indiana bituminous strike | 1927 | nationwide |
| 193,000 | 1967 US truckers strike | 1967 | nationwide |
| 185,000 | 1997 UPS Strike | 1997 | nationwide |
| 180,000 | Bituminous coal miners' strike of 1894 | 1894 | nationwide |
| 175,000 | 1950 US Rail strike | 1950 | nationwide |
| 174,000 | 1946 United Electrical GE strike | 1946 | nationwide |
| 166,300 | 1976 Ford motor strike | 1976 | nationwide |
| 164,000 | 1969–1970 General Electric strike | 1969-70 | nationwide |
| 160,000 | Bituminous Coal Strike of 1977–1978 | 1977–78 | nationwide |
| 160,000 | 1955 General Motors strike | 1955 | nationwide |
| 160,000 | 2023 SAG-AFTRA strike | 2023 | nationwide |
| 159,000 | 1967 Ford Motors strike | 1967 | nationwide |
| 152,000 idled | 1998 General Motors strike | 1998 | Flint, Michigan |
| 150,000 | 1952 Telephone strike | 1952 | nationwide |
| 145,000 | 1980 California construction strikes | 1980 | California |
| 142,000 | 1946 Licensed personal maritime strike | 1946 | nationwide |
| +136,000 | Flint sit-down strike | 1936 | Flint, Michigan |
| 136,000 | 1996 General Motors Strike | 1996 | Dayton, OH |
| 135,000 | 2000 commercial actors strike | 2000 | Hollywood |
| 134,400 | 1943 steelworkers strike | 1943 | Northeastern United States |
| 132,000 | 1946 Unlicensed personal maritime strike | 1946 | nationwide |
| 130,000 | 1900 Anthracite coal strike | 1900 | Eastern Pennsylvania |
| 125,000 | 1957 Western Electric strike | 1957 | nationwide |
| 120,000 | Bituminous Coal Strike of 1974 | 1974 | nationwide |
| 116,000 | 1966 rail strike | 1966 | |
| 116,000 | 1961 Ford Motors strike | 1961 | nationwide |
| 111,400 | 1973 Chrysler strike | 1973 | nationwide |
| 110,100 | 1976 Bituminous coal strike | 1976 | |
| 110,000 | 1970 US truckers strike | 1970 | nationwide |
| 110,000 | 2018–2019 education workers' strikes | 2018–2019 | nationwide |
| 105,000 | 1971 Bituminous coal strike | 1971 | |
| 105,000 | 1958 Dress workers strike | 1958 | New England |
| 102,000 | 2004 SBC Communications workers strike | 2004 | nationwide |
| +100,000 | Great Railroad Strike | 1877 | nationwide |
| +100,000 | 1902 Anthracite coal strike | 1902 | Pennsylvania |
| 100,000's | [1918-1920 New York City rent strikes|1918-20 New York (state)|New York City rent strikes] | 1918-20 | New York City |
| 100,000 | 1947 Iowa one-day general strike | 1947 | Iowa |
| 100,000 | 1872 New York City Eight Hour Day Strike | 1872 | New York City |
| 100,000 | 1973 Chicago construction strike | 1973 | Chicago, IL |
| 95,000 | 1950 Chrysler strike | 1950 | - |
| 90,000 | 1952 Oil workers strike | 1952 | nationwide |
| 85,700 | 1974 US textile workers strike | 1974 | nationwide |
| 85,000 | Verizon Strike | 2000 | nationwide |
| 83,000 | 1948 US Meatpacking strike | 1948 | nationwide |
| 80,000 | 1994 US truckers strike | 1994 | nationwide |
| 80,000 | 1950 Western Electric strike | 1950 | nationwide |
| 78,000 | 1955 Ford Motor strike | 1955 | nationwide |
| 75,000 | 2023 Kaiser Permanente healthcare workers strike | 2023 | |
| 75,000 | 1946 Westinghouse Electric strike | 1946 | Pittsburgh |
| 75,000 | 1948 Chrysler strike | 1948 | Midwestern United States |
| 75,000 | 1958 Ford Motor strike | 1958 | |
| 73,000 | 1973 Pennsylvania Central Transportation strike | 1973 | Northeastern United States |
| 73,000 | 1998 Bell Atlantic strike | 1998 | nationwide |
| 73,000 | 1961 Airline strike | 1961 | nationwide |
| 73,000 | 1943 Pennsylvania Anthracite coal strike | 1943 | Eastern Pennsylvania |
| 70,000 | 1972 Chicago builders strike | 1972 | Chicago |
| 70,000 | Southern California supermarket strike of 2003–2004 | 2003–2004 | Southern California |
| 70,000 | 1951 rail strike | 1951 | nationwide |
| 73,000 | 2007 General Motors strike | 2007 | Detroit, Michigan |
| 72,000 | 1960 Pennsylvania Railroad Co. strike | 1960 | |
| 68,000-85,000 | New England Textile Strike | 1922 | Northeast |
| +67,000 | Little Steel strike | 1937 | nationwide |
| 67,000 | 1980 actors strike | 1980 | nationwide |
| 66,000 | 1968 Bituminous coal strike | 1968 | |
| 65,000 | 1971 Northern and Central California construction strikes | 1971 | California |
| 64,100 | 1974 Western Electric strike | 1974 | |
| 63,000 | 1975 New York City teachers strike | 1975 | New York City |
| 63,000 | 1960 General Electric strike | 1960 | nationwide |
| 63,100 | 1980 Petroleum strike | 1980 | nationwide |
| 62,000 | 1949 Ford Motor Michigan strike | 1949 | Michigan |
| 61,900 | 1975 Bituminous coal strike | 1975 | |
| 60,000 | 1953 California construction strike | 1953 | Northern and Central California |
| 60,000 | 1956 East & Gulf Coast longshoremen strike | 1956 | East & Gulf Coast |
| 59,000 | 1969 UMW coal strike | 1969 | |
| 56,200 | 1976 Rubber workers strike | 1976 | nationwide |
| 56,000 | 1958 Chrysler strike | 1958 | |
| 55,000 | 1978 Southern California retail clerks strike | 1978 | Southern California |
| 54,800 | 1944 Detroit Foremen's Strike | 1944 | Detroit, Michigan |
| 53,940 | New York City Teacher's Strike of 1968 | 1968 | New York City |
| 52,700 | 1975 AFSCME Pennsylvania strike | 1975 | Pennsylvania |
| 52,000 | 1950 International Harvester strike | 1950 | |
| 52,000 | 1959 East & Gulf Coast longshoremen strike | 1959 | East & Gulf Coast |
| +50,000 | Clockmakers' strike | 1910 | New York City |
| 50,000 | 1962 East & Gulf Coast longshoremen strike | 1962 | East & Gulf Coast |
| 50,000 | 1970 Southern California construction strike | 1970 | Southern California |
| 50,000 | 1974 Southern California construction strike | 1974 | Southern California |
| 50,000 | 1980 Southern California construction strike | 1980 | Southern California |
| 50,000 | 1968 Michigan construction strike | 1968 | Michigan |
| 50,000 | 1967 Rubber workers strike | 1967 | |
| 50,000 | 1947 Shipyard strike | 1947 | nationwide |
| 50,000 | 1946 Oakland general strike | 1946 | Oakland, California |
| 50,000 | 1953 Telephone strike | 1953 | |
| 50,000 | 1972 Minneapolis construction contractors strike | 1972 | Minneapolis and surrounding areas |
| 50,000 idled | SS California strike | 1936 | San Pedro, California |
| 49,800 | 2023 United Auto Workers strike | 2023 | nationwide |
| 49,000 | 1969 Oil workers strike | 1969 | |
| 48,000 | 2022 University of California academic workers' strike | 2022 | California |
| 48,000 | 1951 Woolen workers strike | 1951 | East Coast |
| 48,000 | 2018 University of California Medical Centers Strike | 2018 | California |
| 48,000 | 2019 General Motors strike | 2019 | nationwide |
| 47,300 | 1979 United Airlines strike | 1979 | nationwide |
| 47,000 | 2000 L.A. County Workers Strike | 2000 | California |
| 47,000 | 1967 New York City teachers strike | 1967 | New York City |
| 47,000 | 1956 US Glass strike | 1956 | |
| 46,000 | 1968 East & Gulf Coast Stevedoring strike | 1968 | East & Gulf Coast |
| 46,000 | 2011 Verizon Strike | 2011 | nationwide |
| 45,800 | 1969 Bituminous coal strike | 1969 | |
| 45,000 | 1974 Northwest contractors strikes | 1974 | Northwestern United States |
| 45,000 | 1929 New York City Garment Strike | 1929 | New York City |
| 45,000 | 1952 Westcoast lumber strike | 1952 | West Coast of the United States |
| 44,000-60,000 | 1945 Pacific Northwest lumber strike | 1945 | Pacific Northwest |
| 44,000 | 1955 Westinghouse electric strike | 1955 | |
| 44,000 | November 1967 General Motors strike | 1967 | Pontiac, Michigan |
| 43,000 | 1971 International Harvester strike | 1971 | nationwide |
| 41,000 | 1910 Chicago garment workers' strike | 1910–1911 | Chicago |
| 40,400 | 1979 Caterpillar strike | 1979 | |
| 40,000 | 1951 Cotton workers strike | 1951 | Southern United States |
| 40,000 | 1955 International Harvester strike | 1955 | |
| 40,000 | 1965 Glassblower strike | 1965 | |
| 40,000 | 1966 UMW coal strike | 1966 | |
| 40,000 | 2016 Verizon workers' strike | 2016 | East Coast |
| 37,100 | 1979 Westinghouse Electric strike | 1979 | |
| 36,000 | 1973 Caterpillar strike | 1973 | nationwide |
| 35,000 | 1934 West Coast waterfront strike | 1934 | U.S. West Coast |
| 35,000 | International Harvester strike of 1979–1980 | 1979-80 | |
| 33,000 | 1966 New York City transit strike | 1966 | New York City |
| 33,000 | | 1995 | Washington State |
| 32,000 - 34,000 | 2005 New York City transit strike | 2005 | New York City |
| 31,000 | 2019 Stop & Shop strike | 2019 | Massachusetts, Rhode Island and Connecticut |
| 31,000 | 1946 New York City truckers strike | 1946 | New York City & New Jersey |
| 30,000–35,000 | 1938 New York City truckers strike | 1938 | New York City & New Jersey |
| 30,000 | 1952 Packinghouse workers strike | 1952 | |
| 30,000 | Illinois Central shopmen's strike of 1911 | 1911 | Illinois, Mississippi and Texas |
| 30,000 | 2019 Los Angeles Unified School District teachers' strike | 2019 | Los Angeles County, California |
| 30,000 | 1928 New Bedford textile strike | 1928 | New Bedford, Massachusetts |
| 30,000 | 1935 Pacific Northwest lumber strike | 1935 | Pacific Northwest |
| 30,000 | 1912 Lawrence textile strike or "Bread and Roses" strike | 1912 | Lawrence, Massachusetts |
| 27,000 | Boeing Machinists Strike of 2008 | 2008 | Seattle, Washington |
| 26,000 | 1967 Caterpillar strike | 1967 | Colorado, Illinois, Iowa, Ohio and Pennsylvania |
| +25,700 | Florida statewide teachers' strike of 1968 | 1968 | Florida |
| 25,000 - 60,000 | Anti-Rent War and strikes | 1839-45 | Hudson Valley, Upstate New York |
| 24,000 | 1951 Caterpillar strike | 1951 | East Peoria, Illinois |
| 23,000 | 1973 Chicago teachers strike | 1973 | Chicago |
| 20,000 | 1948 Caterpillar strike | 1948 | Peoria, Illinois |
| +20,000 | 1982 garment workers' strike | 1982 | New York City |
| 20,000 | 2019 AT&T strike | 2019 | Southern United States |
| 20,000 | Philadelphia General Strike | 1835 | Philadelphia |
| 20,000 | New England Shoemakers Strike of 1860 | 1860 | Lynn, Massachusetts |
| 20,000-30,000 | New York shirtwaist strike of 1909 | 1909 | Manhattan, New York |
| 19,000 | 1985 Pan Am strike | 1985 | nationwide |
| 17,000 | 1962 New York City newspaper strike | 1962 | New York City |
| 16,000 | 1973 Philadelphia teachers strike | 1973 | Philadelphia |
| 16,000 | Santa Clara cannery strike | 1931 | Santa Clara, California |
| 15,000-16,000 | 1919 NYC Harbor Strike | 1919 | New York City |
| 15,000 | 1836 Mill Women's Strike | 1836 | Lowell, Massachusetts |
| 15,000 | Westmoreland County coal strike of 1910–1911 | 1910–1911 | Westmoreland County, Pennsylvania |
| 15,000 | 1920 Alabama coal strike | 1920 | Alabama |
| 15,000 | 1957 Long Island strike | 1957 | Long Island, New York |
| 15,000 | Boeing Strike of 1948 | 1948 | Seattle, Washington |
| 15,000 | 1926 Passaic textile strike | 1926 | Passaic, New Jersey |
| 15,000 | 1835 New England Mill Strike | 1835 | New England |
| 14,000 | Copper Country strike of 1913–1914 | 1913–1914 | Upper Michigan |
| 14,000 | 1994 Caterpillar strike | 1994 | Illinois, Pennsylvania and Colorado |
| 14,000 | Bay View massacre | 1886 | Milwaukee, Wisconsin |
| 13,000 | Air traffic controllers' strike | 1981 | nationwide |
| 12,600 | 1973 Detroit teachers strike | 1973 | Detroit |
| +12,000 | Tampa cigar makers' strike of 1910–11 | 1910–1911 | Tampa, Florida |
| 12,000 | 1938 San Antonio pecan shellers strike | 1938 | San Antonio |
| 12,000 minimum | Tool and die strike of 1939 | 1939 | Detroit, Michigan |
| 12,000 | 1951 Aliquippa steelworkers strike | 1951 | Aliquippa, Pennsylvania |
| 12,000 | Colorado Coalfield War | 1913 | Ludlow, Colorado |
| 12,000 | Longshore Strike (1971, U.S.) | 1971 | U.S. West Coast Hawaii and British Columbia |
| 12,000 | 2007–2008 Writers Guild of America strike | 2007–2008 | Hollywood, California |
| 12,000 | 1973 Cleveland teachers strike | 1973 | Cleveland |
| 12,000 | September 1967 General Motors strike | 1967 | Dayton, Ohio |
| 11,600 | 2021 Washington state carpenters strike | 2021 | Washington |
| 11,500 | 2023 Writers Guild of America strike | 2023 | nationwide |
| 10,000-14,000 | 1933 Detroit auto strike | 1933 | Detroit, Michigan |
| 10,500 | Hollywood Black Friday | 1945 | Hollywood, California |
| 10,000 at least | Auto-Lite strike | 1934 | Toledo, Ohio |
| 10,000-30,000 | 1917 Twin Cities streetcar strike | 1917 | Minneapolis–Saint Paul, Minnesota |
| +10,000 | Delano grape strike | 1965–70 | Delano, California |
| 10,000 | 1907 San Francisco streetcar strike | 1907 | San Francisco, California |
| 10,000 | 2021 John Deere strike | 2021 | Nationwide |
| 10,000 | Goodyear strike | 1948 | Akron, Ohio |
| 10,000 | Pacific Northwest lumber strike | 1935 | U.S. Pacific Northwest |
| 10,000 | 1907 New York City rent strike | 1907 | New York City |
| 10,000 | Cigar makers' strike of 1877 | 1877–1878 | New York City |
| 10,000 idle | 1978 New York City newspaper strike | 1978 | New York City |
| 10,000 | Thibodaux massacre (Sugar cane workers' strike) | 1887 | Lafourche Parish, Louisiana |
| 10,000 | Battle of Blair Mountain | 1921 | Logan County, West Virginia |
| 9,000 | 1988 Writers Guild of America strike | 1988 | Hollywood, California |
| 9,000 | 2023 Rutgers University strike | 2023 | New Jersey |
| 8,500 | 1981 Writers Guild of America strike | 1981 | Hollywood, California |
| +8,400 | Colorado Coal Strike | 1927 | Serene, Colorado |
| 8,000 | Tampa cigar makers' strike of 1931 | 1931 | Tampa, Florida |
| 8,000 | 1923 San Pedro maritime strike | 1923 | San Pedro, Los Angeles, California |
| 8,000 | Pressed Steel Car strike of 1909 | 1909 | McKees Rocks, Pennsylvania |
| 7,700 | Marriott Hotels strike | 2018 | Bethesda, Maryland |
| 7,500 | Coal miners' strike of 1873 | 1873 | Northeastern Ohio, Northwestern Pennsylvania |
| 7,500 | 1935 Gulf Coast longshoremen's strike | 1935 | U.S. Gulf Coast |
| 7,100 | 1953 Milwaukee brewery strike | 1953 | Milwaukee |
| 7,000 | 1949 New York City brewery strike | 1949 | New York City |
| 7,000 | Tompkins Square Riot | 1874 | New York City |
| 6,500 | 1912 New York City waiters' strike | 1912 | New York City |
| 6,500 | Homestead strike | 1892 | Homestead, Pennsylvania |
| 6,550 | 2015 United Steel Workers Oil Refinery Strike | 2015 | California, Indiana, Kentucky, Ohio, Texas and Washington |
| +6,000 | Remington Rand strike of 1936–1937 | 1936–37 | New York City |
| +6,000 | US Maritime Strike of 1921 | 1921 | nationwide |
| +6,000 | 1911 Grand Rapids furniture workers strike | 1911 | Grand Rapids, Michigan |
| 6,000 | Salad Bowl strike | 1970–71 | nationwide |
| 5,800 | Harlan County War | 1931 | Harlan County, Kentucky |
| 5,000 | Newsboys Strike | 1899 | New York, New York |
| 5,000 | Ford Hunger March | 1932 | Detroit, Michigan |
| 5,000 | Imperial Valley lettuce strike of 1930 | 1930 | Imperial Valley, California |
| +4,500 | Philadelphia Transit Strike | 1944 | Philadelphia, Pennsylvania |
| 4,500 | 2022 Minneapolis teacher's strike | 2022 | Minneapolis |
| 4,300 | 2020 Bath shipbuilders strike | 2020 | Bath, Maine |
| 4,000 - 5,000 | 1937 Lewiston–Auburn shoe strike | 1937 | Lewiston, Maine and Auburn, Maine |
| 4,000 | Chrysler wildcat strike | 1968 | Detroit, Michigan |
| +4,000 | Southern California drywall strike | 1992 | Southern California |
| 3,700 | 2023 Portland Association of Teachers strike | 2023 | Portland, Oregon |
| 3,500 | Coeur d'Alene labor strike | 1892 | Coeur d'Alene, Idaho |
| 3,200 | 2025 Boeing machinists' strike | 2025 | Greater St. Louis, Missouri/Illinois |
| 3,000 | St. Louis streetcar strike of 1900 | 1900 | St. Louis, Missouri |
| 3,000 | Chinese Labor Strike of 1867 | 1867 | Sierra Nevada, California |
| 3,000 | Guilford Transportation Industries railroad workers' strike | 1986 | North Billerica, Massachusetts |
| 3,000 | 2021 Columbia University strike | 2021 | New York City |
| 3,000 | 1881 Atlanta washerwomen strike | 1881 | Atlanta |
| 2,900 | 2021 Virginia Volvo Trucks strike | 2021 | Dublin, Virginia |
| 2,600 | San Francisco newspaper strike of 1994 | 1994 | San Francisco, California |
| 2,500 | Detroit Newspaper Strike | 1995–97 | Detroit, Michigan |
| 2,400 | National Union Healthcare Workers (NUHW) against Kaiser Permanente | 2024-25 | Southern California |
| 2,300 | 2015 Kohler Strike | 2015 | Kohler, Wisconsin |
| 2,250 | Leadville miners' strike | 1896 | Leadville, Colorado |
| 2,200 | 2021 New York University strike | 2021 | New York City |
| +2,300 | Arizona Copper Mine Strike of 1983 | 1983 | Greenlee County, Arizona |
| 2,100 | Boston cigar makers' strike of 1919 | 1919 | Boston |
| 2,100 | 2020 Michigan graduate students strike | 2020 | Ann Arbor, Michigan |
| 2,000 | 2021 Mercy Hospital strike | 2021 | Buffalo, New York |
| 2,000 | 1835 Paterson textile strike | 1835 | Paterson, New Jersey |
| +2,000 | Puget Sound fishermen's strike of 1949 | 1949 | Puget Sound, Washington |
| +2,000 | Pittston Coal strike | 1989–90 | Pittston, Pennsylvania |
| 2,000 | 1904 New York City Rent Strike | 1904 | New York City |
| 1,000s | 2010 Georgia prison strike | 2010 | Georgia |
| 1,000s | 1945–1946 Charleston Cigar Factory strike | 1945–46 | Charleston, South Carolina |
| 1,000s | Bayonne refinery strikes | 1915–16 | Bayonne, New Jersey |
| 1,850 | Paterson silk strike | 1913 | Paterson, New Jersey |
| 1,800 | Loray Mill strike | 1929 | Gastonia, North Carolina |
| 1,700 | 1973 New York City gravediggers' strike | 1973 | New York City |
| 1,500 | 1977–78 Coors strike | 1977–78 | Golden, Colorado |
| 1,500 | Atlanta transit strike of 1950 | 1950 | Atlanta |
| 1,500 | 1985–86 Hormel strike | 1985–86 | Austin, Minnesota |
| 1,400 | 2021 Kellogg's strike | 2021 | Nationwide |
| 1,400 | 2021 Hunts Point Produce Market strike | 2021 | New York City |
| 1,325 | 2003 Broadway Musicians Strike | 2003 | New York City |
| 1,300 | Memphis sanitation strike | 1968 | Memphis, Tennessee |
| 1,300 | 2021 Allegheny Technologies strike | 2021 | Northern United States |
| 1,300 | 1977 Atlanta sanitation strike | 1977 | Atlanta |
| +1,200 | Oxnard strike of 1903 | 1903 | Oxnard, California |
| 1,200 | International Paper strike | 1987 | Corinth, New York |
| 1,100 | Tacoma nurses strike 2014 | 2014 | Tacoma and Lakewood, Washington |
| 1,100 | 2021–2023 Warrior Met Coal strike | 2021–2023 | Alabama |
| 1,100 | 2007 Orange County transit strike | 2007 | Orange, California |
| 1,100 | 1929 New Orleans streetcar strike | 1929 | New Orleans, Louisiana |
| +1,000 | 1934 Kohler strike | 1934 | Sheboygan, Wisconsin |
| 1,000 | 1985–1987 Watsonville Cannery strike | 1985–87 | Watsonville, California |
| 1,000 | 1913 El Paso smelters' strike | 1913 | El Paso, Texas |
| 1,000 | 1916–1917 northern Minnesota lumber strike | 1916–1917 | Minnesota |
| 1,000 | 2021 Nabisco strike | 2021 | Nationwide |
| +900 | 2021 Cook County nurses strike | 2021 | Cook County, Illinois |
| 855 | Hayward teachers strike | 2007 | Hayward, California |
| +800 | 2020 University of Illinois Hospital strikes | 2020 | Chicago |
| 800 | 2021 Saint Vincent Hospital strike | 2021 | Worcester, Massachusetts |
| 800 | 1828 Mill Women's Strike | 1828 | New Hampshire |
| 800 | Jeffboat wildcat strike | 2001 | Jeffersonville, Indiana |
| 800 | 2012 Ports of Los Angeles and Long Beach strike | 2012 | Los Angeles and Long Beach, California |
| 700 | Pacific Electric Railway strike of 1903 | 1903 | Los Angeles |
| 700 | 1981 Schlitz strike | 1981 | Milwaukee |
| 700 | 1985–1986 New Bedford fishermen's strike | 1985–86 | New Bedford, Massachusetts |
| 700 | 2007 Freightliner wildcat strike | 2007 | Portland, Oregon |
| 700 | 1964–1965 Scripto strike | 1964–65 | Atlanta |
| 664 | 1912–1913 Little Falls textile strike | 1912–1913 | Little Falls, New York |
| +600 | 1934–35 Milwaukee sales clerks' strike | 1934–35 | Milwaukee |
| 600 | 2021 Frito-Lay strike | 2021 | Topeka, Kansas |
| 560 | Wright State University 2019 faculty strike | 2019 | Dayton, Ohio |
| 550 | Frontier Hotel Culinary Workers | 1991 | Las Vegas |
| 515 | Buffalo switchmen's strike | 1892 | Buffalo, New York |
| 420 | 2021 Heaven Hill strike | 2021 | Bardstown, Kentucky |
| 400 | 2019 Alaska ferry workers strike | 2019 | Alaska |
| 400 | 2020–2021 Alabama aluminum plant strike | 2020–2021 | Muscle Shoals, Alabama |
| 400 | Texas farm workers' strike | 1966 | Texas |
| 400 at least | Weight Strike | 1899 | Ybor City, Tampa, Florida |
| 382 | 2018 DeKalb County School District bus drivers' strike | 2018 | DeKalb County, Georgia |
| 375 | 2020 Santa Cruz graduate students' strike | 2020 | Santa Cruz, California |
| 350 | 2007 Broadway Stagehand Strike | 2007 | New York City |
| 328 | Port Chicago mutiny | 1944 | Port Chicago, California |
| 300–400 | Lattimer massacre | 1897 | Lattimer, Pennsylvania |
| 300-400 | 1914–1915 Fulton Bag and Cotton Mills strike | 1914–1915 | Atlanta |
| 300 | Collar Laundry Union strike | 1864 | Troy, New York |
| 250 | 2022–2023 HarperCollins strike | 2022–2023 | New York City |
| 250 | 2003 June 15 Hospitality workers at the Congress Plaza Hotel. | 2003 | Chicago, Illinois |
| 250 | 1949 Calvary Cemetery strike | 1949 | New York City |
| 250 | Coeur d'Alene labor confrontation | 1899 | Coeur d'Alene, Idaho |
| 211 | 1968 St. Petersburg, FL sanitation strike | 1968 | St. Petersburg, Florida |
| +200 | Disney animators' strike | 1941 | Burbank, California |
| +200 | 2018 Alabama Coca-Cola strike | 2018 | Alabama and Mississippi |
| 225 | 1907 Skowhegan textile strike | 1907 | Skowhegan, Maine |
| 200 | 2021 St. Paul Park refinery strike | 2021 | St. Paul Park, Minnesota |
| 175 | 1835 Washington Navy Yard labor strike | 1835 | Washington Navy Yard, Washington D.C. |
| 175 | 1983 Greyhound Bus Lines strike in Seattle | 1983 | Seattle |
| 156 | 2021 St. Charles Bend strike | 2021 | Bend, Oregon |
| 120 | 2018 Atlanta sanitation strike | 2018 | Atlanta |
| 100 | University of Miami Justice for Janitors campaign | 2006 | Coral Gables, Florida |
| 80 | Georgia Railroad strike | 1909 | Georgia |
| 75 | Camp Dump strike | 1883 | Omaha, Nebraska |
| 75 | 1937 Fleischer Studios strike | 1937 | New York City |
| 40 | Indentured Servants' Plot | 1661 | Virginia colony |
| 26 | 2020 New Orleans sanitation strike | 2020 | New Orleans |
| 23 | Century Airlines pilots' strike | 1932 | Chicago, Illinois |
| - | Minneapolis general strike of 1934 | 1934 | Minneapolis, Minnesota |
| - | Great Northern Railway strike | 1894 | nationwide |
| - | Gulf Coast maritime workers' strike | 1936 | U.S. Gulf Coast |
| - | Indianapolis streetcar strike of 1913 | 1913 | Indianapolis, Indiana |
| - | Los Angeles streetcar strike of 1919 | 1919 | Los Angeles, California |
| - | Carbon County Strike | 1903 | Carbon County, Utah |
| - | Colorado Labor Wars, Western Federation of Miners | 1903–1904 | Colorado |
| - | 1979 Boston University strike | 1979 | Boston |
| - | 2021 Oregon Tech strike | 2021 | Oregon |
| - | 2016–2017 video game voice actor strike | 2016–2017 | Los Angeles, California |
| - | 2018 Taylorsville Georgia-Pacific strike | 2018 | Taylorsville, Mississippi |
| - | California agricultural strikes of 1933 | 1933 | California |
| - | 1934 New York hotel strike | 1934 | New York City |
| - | Strike for Black Lives | 2020 | Nationwide |
| - | Polish craftsmen's strike | 1619 | Jamestown |
| - | 2021 Kaiser Permanente strike | 2021 | Nationwide |
| - | 1834 Mill Women's Strike | 1834 | Lowell, Massachusetts |
| - | 1948 Miami Garment workers strike | 1948 | Miami, Florida |
| - | North Adams strike | 1870 | North Adams, Massachusetts |
| - | Boston garment worker strike | 1907 | Boston |
| - | Cotton pickers' strike of 1891 | 1891 | Lee County, Arkansas |
| - | Upper Peninsula miners' strike | 1865 | Marquette, Michigan |
| - | Louisiana-Texas Lumber War of 1911–1912 | 1911–1912 | Eastern Louisiana |
| - | Paint Creek–Cabin Creek strike of 1912 | 1912 | Kanawha County, West Virginia |
| - | Pensacola streetcar operators' strike | 1908 | Pensacola, Florida |
| - | U.S. Steel recognition strike of 1901 | 1901 | Homestead, Pennsylvania |
| - | Coal Creek War | 1891 | Anderson County, Tennessee |
| - | Newsboys' strike | 1899 | New York City |
| - | Seattle Fishermen halibut strike of 1912 | 1912–13 | Seattle, Washington |
| - | 1916 Atlanta streetcar strike | 1916 | Atlanta |
| - | Denver streetcar strike of 1920 | 1920 | Denver, Colorado |
| - | 1992 CSX railroad strike | 1992 | nationwide |
| - | 1982 animators' strike | 1982 | Greater Los Angeles |
| - | 1960 Writers Guild of America strike | 1960 | Hollywood, California |
| - | St. John's University strike of 1966–67 | 1966–67 | New York City |
| - | 2007–2008 CBS News writers strike | 2007–2008 | New York City |
| - | 1919 Actors' Equity Association strike | 1919 | New York City |
| - | 1942-43 musicians' strike | 1942–43 | nationwide |
| - | 1981 Milwaukee Police strike | 1981 | Milwaukee |
| - | Boston Police Strike | 1919 | Boston, Massachusetts |
| - | 1971 NYPD Work Stoppage | 1971 | New York City |
| - | 1995 NBA lockout | 1995 | nationwide |
| - | 1996 NBA lockout | 1996–97 | nationwide |
| - | 2011 NBA lockout | 2011 | nationwide |
| - | 1998–99 NBA lockout | 1998–99 | nationwide |
| - | 1968 NFL strike/lockout | 1968 | Florida |
| - | 2011 NFL lockout | 2011 | nationwide |
| - | 2012 NFL referee lockout | 2012 | nationwide |
| - | 1982 NFL strike | 1982 | nationwide |
| - | 1974 NFL strike | 1974 | nationwide |
| - | 1987 NFL strike | 1987 | nationwide |
| - | 1992 NHL strike | 1992 | nationwide |
| - | 1994–95 NHL lockout | 1994–95 | nationwide |
| - | 2012–13 NHL lockout | 2012–13 | nationwide |
| - | 2004–05 NHL lockout | 2004–2005 | nationwide |
| - | 1990 Major League Baseball lockout | 1990 | nationwide |
| - | 1994–95 Major League Baseball strike | 1994–95 | nationwide |
| - | 1981 Major League Baseball strike | 1981 | nationwide |
| - | 2010 Major League Soccer lockout/strike | 2010 | nationwide |
| - | 1972 Major League Baseball strike | 1972 | nationwide |
| - | 1985 Major League Baseball strike | 1985 | nationwide |
| - | Major Indoor Soccer League lockout | 1986 | nationwide |
| 47,000 | 2024 United States port strike | 2024 | East Coast and Gulf Coast |
| 2000 | 1999 Teamsters Overnite Transportation drivers strike | 1999-2002 | nationwide |