| Name | Class year | School/ degree | Notability | Reference |
| 1989 | SFS | President of Oberlin College, 2017–present; president of Cedar Crest College, 2008–2017 | |
| 1967, 1970 | SFS, Law | President of Rutgers University, 2012–2020; president of Thomas Jefferson University, 2004–12; provost of the University of Pennsylvania, 1998–2004 | |
| Rev. | 1976 | Col | President of Saint Louis University, 1987–2013 | |
| Rev. | 1979 | MSB | President of Rockhurst University, 2006–present | |
| 1980, 1994 | Grad, Col | President of Georgetown University, 2001–2024 | |
| Rev. | 1938–1939* | Col | President of Fairfield University, 1973–79; president of Saint Louis University, 1979–87 | |
| Edward T. Foote II | | Law | President of the University of Miami, 1981–2001; dean of Washington University School of Law, 1973–1980 | |
| 1992 | LL.M. | Chancellor of Oklahoma State Regents for Higher Education, 2021–present; former president of Emporia State University, 2016–2021; former Walmart vice president/legal counsel | |
| 1994 | Law | Chancellor of University of North Carolina at Chapel Hill, 2024–present | |
| 1979 | Grad | 16th president of the Massachusetts Institute of Technology, 2004–12; provost of Yale University, 2002–2004; dean of Yale Graduate School of Arts and Sciences, 1998–2002 | |
| 1961 | MSB | President of Mount St. Mary's University, 1994–2003 | |
| Rev. | 1981 | Grad | President of Loyola University Maryland, 2005–present | |
| 2005 | Law | President of Berklee College of Music, 2025–present | |
| Very Rev. | 1790s | Col | President of Georgetown College, 1809; vicar general of the Diocese of Philadelphia | |
| Rev. Kevin F. O'Brien | 1988 | Col | President of Santa Clara University, 2019–present | |
| Rev. | 1956 | Col | President of Georgetown University, 1989–2001 | |
| Rev. | 1981 | Col | President of Marquette University, 2011–13; president of the University of Scranton, 2003–11, 2018–present | |
| Rev. | 1868–1872* | | President of the University of San Francisco, 1876–80; president of Santa Clara College, 1880–83, 1888–93 | |
| 1983 | Col | President of Franklin & Marshall College, 2011–2018 | |
| 1954, 1955 | Law, LL.M. | President of Southern Methodist University, 1987–94 | |
| 1971 | Grad | President of Heritage University; MacArthur Fellow | |
| 1984 | SFS | Senior associate dean of Harvard Business School Online; president of Barnard College, 2008–2017 | |
| 1977 | SFS | Chancellor and president of Syracuse University, 2014–present; dean of Washington University School of Law, 2005–2013; dean of Vanderbilt University Law School, 1997–2005 | |
| 1969 | SFS | President of the University of Illinois at Urbana–Champaign, 2005–09 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1935 | SFS | President of Panama, 1955–56 | |
| 1998 | MSFS | President of the European Commission, 2004–2014; prime minister of Portugal, 2002–04 | |
| 1989 | MPP | President of Costa Rica, 2010–14 | |
| 1968 | SFS | President of the United States, 1993–2001 | |
| 1968 | MSB | President of El Salvador, 1989–94 | |
| 1995 | MSFS | King of Spain, 2014–present | |
| 1992 | MSB | Prime Minister of Lebanon, 2009–2011; prime minister of Lebanon, 2016–2020 | |
| 1987 | MSFS | King of Jordan, 1999–present | |
| 1934 | Law | President of the United States, 1963–69 | |
| 1982 | SFS | Tripartite President of Bosnia, 2006–present | |
| | SFS | President of Colombia, 1974–78 | |
| 1968 | SFS | President of the Philippines, 2001–10 | |
| 2011 | MPP | President of Colombia, 2018–2022 | |
| 1929 | SFS | President of Ecuador, 1948–52; 4th Secretary General of the Organization of American States, 1968–75 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1963 | SFS | Governor of New Mexico, 1983–87 | |
| 1889 | Law | Governor of South Carolina, 1911–15; United States senator, 1925–31 | |
| 1937 | Law | Governor of Delaware, 1953–60; United States senator, 1961–73; member of the United States House of Representatives, 1947–53 | |
| | Col | Governor of Maryland, 1876–80; great-grandson of Charles Carroll of Carrollton | |
| 1964 | Law | Governor of Delaware, 1985–92; United States representative, 1993–2011 | |
| 1949, 1951 | Col, Law | First appointed governor of American Samoa, 1956–61; first elected governor of American Samoa, 1978–85, 1989–93 | |
| 1981 | Col | Governor of Kansas, 2018–2019 | |
| 1979 | Law | Governor of Indiana, 2005–13; president of Purdue University | |
| 1938 | Law | Governor of Rhode Island, 1959–61 | |
| 1931 | Law | Governor of Ohio, 1959–63 | |
| 1910 | Law | Governor of Rhode Island, 1923–25 | |
| 1982 | SFS | Governor of the Commonwealth of Puerto Rico, 2009–13 | |
| 1900 | Law | Governor of Rhode Island, 1907–09 | |
| 1966 | Col | Governor of Oklahoma, 1995–2003; president and CEO of the American Bankers Association | |
| 1978 | Law | Governor of New Hampshire, 2005–13 | |
| 1986 | Law | Governor of Virginia, 2014–18; chairman of the Democratic National Committee | |
| 1981 | Law | Governor of New Jersey, 2002–04 | |
| 1972 | Law | Governor of New Hampshire, 1993–97 | |
| 1915* | Law | First democratically elected governor of Puerto Rico, 1949–65; known as the "father of modern Puerto Rico" | |
| 1957 | Law | Governor of Rhode Island, 1973–77 | |
| 1822* | Col | Governor of Maryland, 1845–1848, U.S. senator from Maryland, 1850–1857 | |
| 1971 | SFS | Governor of Illinois, 2009–15 | |
| 1918 | Col | Governor of Connecticut, 1948–49 | |
| 1972 | Law | Governor of Alabama, 1999–2003 | |
| 1953 | Law | Governor of Washington, 1981–85 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1851 | Law | Secretary of War, 1869–76 | |
| 1895 | Law | Secretary of the Treasury, 1907–09; first Secretary of Commerce and Labor, 1903–04; Postmaster General, 1905–07 | |
| 1974 | Grad | Secretary of Defense, 2006–11; Director of Central Intelligence, 1991–93; president of the Boy Scouts of America; president of Texas A&M University, 2002–06 | |
| 1961 | Grad | Secretary of State, 1981–82; Supreme Allied Commander Europe, 1974–79; White House Chief of Staff, 1973–74; CEO, United Technologies | |
| 1968 | Law | Secretary of Commerce, 1996–97; U.S. Trade Representative, 1993–96 | |
| 1984 | SSP | Secretary of Homeland Security, 2017; White House Chief of Staff, 2017–2019 | |
| 1975 | Law | Secretary of the Treasury, 2013–2017; White House Chief of Staff, 2012–13; director, Office of Management and Budget, 1998–2001, 2010–12; Deputy Secretary of State for Management and Resources, 2009–10 | |
| 1996 | MSFS | United States Secretary of Veterans Affairs, 2021–2025; White House Chief of Staff, 2013–2017; Deputy National Security Advisor, 2010–2014 | |
| 1994 | SFS | Secretary of Homeland Security, 2017–2019 | |
| 1957* | Law | Secretary of Defense, 1975–77, 2001–06; White House Chief of Staff, 1974–75; United States Permanent Representative to NATO, 1973–74; director of the Office of Economic Opportunity, 1969–70; United States representative from Illinois, 1963–69 | |
| 1992 | LL.M. | Secretary of Veterans Affairs, 2018–2021; Under Secretary of Defense for Personnel and Readiness, 2017–2018, Assistant Secretary of Defense for Legislative Affairs, 2006–2009 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1914 | Law | Director of the National Park Service, 1929–33; conservationist; recipient of the Presidential Medal of Freedom | |
| 1967 | Col | Deputy Secretary of the Treasury, 1993–94, founder and senior chairman of Evercore | |
| 1984 | Law | Executive Director of Pension Benefit Guarantee Corporation, 2004–06 | |
| 1986 | SFS | Secretary of the Navy | |
| 1966 | Law | Commissioner of the U.S. Customs and Border Protection, 2001–05; Administrator of the Drug Enforcement Administration, 1990–93; Judge of the U.S. District Court for the Central District of California, 1989–90 | |
| | GAI | National Oceanic and Atmospheric Administration Commissioned Officer Corps rear admiral; director, NOAA Commissioned Officer Corps | |
| | Law | Assistant secretary of Labor for Employee Benefits, 2007–09 | |
| 1987 | SFS | Solicitor general of the United States, 2004–08 | |
| 1977 | SFS | Under Secretary of State for Democracy and Global Affairs, 2001–09 | |
| 1970 | Law | Assistant Secretary of Energy for Domestic and International Energy Policy; Vermont attorney general, 1981–85 | |
| 1978 | Law | Undersecretary of Defense for Policy, 2001–05 | |
| 1993 | Law | Assistant Secretary of Labor for Occupational Safety and Health, 2006–08 | |
| 1991 | Law | Director of the Peace Corps, 1995–99; White House Deputy Chief of Staff, 1993; president of Hobart and William Smith Colleges, 1999–present | |
| 1981 | SFS | Assistant Secretary of State for Consular Affairs, 2002–08; CEO, International Centre for Missing and Exploited Children | |
| 1982 | Grad | Assistant Secretary of State for International Organization Affairs, 2002–15; Vice President of Foreign and Defense Policy Studies at The Heritage Foundation | |
| 1985 | Grad | Deputy Secretary of Homeland Security, 2005–07 | |
| 1979 | Law | Acting Director of the Office of Personnel Management, 2013; Judge of the United States Court of Federal Claims, 2013–present | |
| 1971 | SFS | Under Secretary of State for Management, 2007–2017 | |
| 1977 | Law | Acting U.S. Secretary of the Treasury, 2006; Deputy Secretary of the Treasury, 2005–09; United States Ambassador to Germany, 1991–93; Undersecretary of State for Political Affairs, 1989–91 | |
| 1920, 1934 | Col, Law | Director of the Bureau of the Budget, 1950–53 | |
| 1999 | Law | Deputy Secretary of Homeland Security, 2009–13; CEO, Council on CyberSecurity | |
| 1973 | Col | President of the Overseas Private Investment Corporation; chairman of Mosbacher Energy Company | |
| 1971 | Col | Administrator of the U.S. Agency for International Development, 2001–06; U.S. Special Envoy to Sudan, 2006–07; chairman of the Massachusetts Turnpike Authority, 2000–01; chairman of the Massachusetts Republican Party, 1980–87; member of the Massachusetts House of Representatives, 1975–87 | |
| Jerome Powell | 1979 | Law | 16th Chair of the Federal Reserve | |
| 1993 | Law | Chairman of the Federal Communications Commission, 2001–2005; president of the National Cable & Telecommunications Association, 2011–present | |
| 1986 | SFS | Assistant Secretary of State for Legislative Affairs, 2008–09 | |
| 1962 | Col | Commissioner of Internal Revenue, 1997–2002 | |
| 1988 | MSFS | Assistant Secretary of Defense for Special Operations/Low Intensity Conflict & Interdependent Capabilities, 2011–13; Assistant Secretary-General for Mission Support, 2001–03; first United States ambassador-at-large for Counterterrorism, 1998–2000 | |
| 1999 | Law | Commissioner of Internal Revenue, 2008–12 | |
| | | Under Secretary of the Interior, 1938–39; gave his name to the Slattery Report | |
| 1973 | Col | Governor of the Federal Reserve, 2009–2017 | |
| 1969 | Law | Solicitor general of New York, 2007–present; acting solicitor general of the United States, 2001; principal deputy solicitor general of the United States, 1998–2001 | |
| 1986 | Law | Assistant attorney general for the Antitrust Division, 2009–11; Federal Trade Commissioner, 1994–97 | |
| 1967 | MA | Acting deputy Archivist of the United States, 1986–1987; deputy Archivist of the United States, 1988–1993 | |
| 1975 | SFS | Assistant Secretary of State for Near Eastern Affairs, 2005–08 | |
| 1962 | LL.M. | Chairman of the Federal Communications Commission, 1974–77; founding partner of Wiley Rein & Fielding | |
| Name | Class year | School/ degree | Notability | Reference |
| 1971 | Law | White House Director of Intergovernmental Affairs, 2014–17; lieutenant governor of Kentucky, 2011–14; mayor of Louisville, Kentucky, 1986–99, 2003–11 | |
| 1978 | SFS | Chief of Staff to Vice President Dick Cheney, 2005–09 | |
| 2008 | Law | Press secretary to Vice President Joe Biden, 2009–2011 | |
| 1982 | SSP | White House Chief Strategist and Senior Counselor to the President, 2017 | |
| 1961 | Col | Advisor to Presidents Richard Nixon, Gerald Ford, and Ronald Reagan; White House Communications Director, 1985–87; nationally syndicated political pundit; a frequent commentator on The McLaughlin Group | |
| 1997 | Law | Assistant to the President for Special Projects, 2010; communications director of the U.S. Treasury, 2009–10; chief spokesperson for the Obama-Biden Transition Project, 2008–09; chief of staff to Michelle Obama, 2008 presidential election campaign | |
| | | Principal Deputy Press Secretary for the Biden administration | |
| 1965 | Law | White House Counsel to President Richard Nixon during the Watergate affair, 1970–73 | |
| 1983 | Col | White House Chief of Staff, 2021–2023; Chief of Staff to Vice President Joe Biden, 2008–11; Assistant to the President and Chief of Staff to Vice President Al Gore, 1995–99; U.S. Ebola Response Coordinator, 2014–15 | |
| 1920, 1934 | Col, Law | Director of the Bureau of the Budget, 1950–53 | |
| 1982 | Col | White House Press Secretary, 1998–2000 | |
| 1985 | Grad | Press secretary to President Clinton, 1995–98 | |
| Kayleigh McEnany | 2010 | SFS | White House Press Secretary, 2020–2021 | |
| 1980 | Law | White House Counsel to President Clinton, 1999–2001 | |
| 1991 | Col | Assistant to the President and Deputy National Security Advisor for Iraq and Afghanistan, 2005–07 | |
| 1998 | Col | White House Communications Director, 2009–13; Senior Advisor to President Obama, 2013–15 | |
| 1971, 1975 | Col, Law | White House Counsel to President Bill Clinton, 1995–96 | |
| 1996 | Law | White House Counsel to President Obama, 2011–2014 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1959 | Grad | President, Center for the Study of the Presidency and Congress; United States Permanent Representative to NATO, 1983–87; co-founder of Center for Strategic and International Studies; advisor to President Ronald Reagan | |
| 1977 | Col | United States Ambassador to Costa Rica, 2009–2013 | |
| 1980 | SFS | United States Ambassador to Albania, 2010–14 | |
| 1952, 1953 | SFS, Grad | United States Ambassador to Brazil, 1983–86; United States Ambassador to Colombia, 1977–80 | |
| 1968 | SFS | United States Ambassador to Uruguay, 1997–2001 | |
| 1987 | Law | United States Ambassador to Portugal, 1994–97; senior advisor to U.S. Secretary of State Madeleine Albright; Special Representative for Global Partnerships | |
| 1962 | SFS | United States Ambassador to Lebanon, 2001–04 | |
| 1921 | SFS | United States Ambassador to Paraguay, 1944–47; United States Ambassador to Colombia, 1947–51; United States Ambassador to Cuba, 1951–53; United States Ambassador to Chile, 1953–56; United States Ambassador to Argentina, 1956–60 | |
| 1976 | MSFS | United States Ambassador to Liberia, 2002–05 | |
| 1950 | SFS | United States Ambassador to Portugal, 1978–82; United States Ambassador to Ecuador, 1976–78 | |
| 1976 | SFS | United States Special Envoy to Sudan, 2017–present; United States Special Envoy to Sudan and South Sudan, 2013–2017; United States Ambassador to Ethiopia, 2010–13; United States Ambassador to Zambia, 2008–10; United States Ambassador to Liberia, 2005–08 | |
| 1988 | SFS | United States Ambassador to Mongolia, 2012–present | |
| 1981 | SFS | United States Ambassador to Lebanon, 2010–13; United States Chargé d'Affaires a.i to Syria, 2008–10 | |
| 1982 | Grad | United States Permanent Representative to NATO, 2009–13 | |
| 1832 1859 | Grad Law | First person of color to become U.S. Atmbassador of Costa Rica and Nicaragua, 1859–1861 | |
| 1960 | SFS | United States Ambassador to Israel, 1993–94; United States Ambassador to Syria, 1988–91; Assistant Secretary of State for Near Eastern Affairs, 1991–93; founding director of the James A. Baker III Institute for Public Policy at Rice University | |
| 1957 | SFS | United States Ambassador to Costa Rica, 1997–2001; United States Ambassador to Uruguay, 1993–97 | |
| 1971 | SFS | United States Ambassador to Angola, 2004–07 | |
| 1879 | Col | United States Ambassador to Denmark, 1907–18 | |
| 1995 | Law | United States Ambassador to Poland, 2009–12 | |
| 1989 | Law | United States Ambassador to Denmark, 2009–13 | |
| 1990 | Law | United States Ambassador to Croatia, 1993–98; United Nations Representative in East Timor, 2000–01; Member of the Vermont Senate, 2011–15 | |
| 1978 | Law | United States Ambassador to Morocco, 1994–98 | |
| 1975 | MSFS | United States Ambassador to Romania, 2009–12 | |
| 1988 | Grad | United States Ambassador to Kenya, 2011–12; Major General, United States Air Force | |
| 1983 | SFS | United States Ambassador to Pakistan, 2015–present; United States Ambassador to Lebanon, 2013–15; United States Special Envoy for Middle East Peace, 2011–13; United States Ambassador to Jordan, 2004–08 | |
| 1985 | SFS | United States Ambassador to the Democratic Republic of the Congo, 2018–present; United States Ambassador to Chile, 2014–2016; Assistant Secretary of State for Public Affairs, 2011–2013 | |
| S. Fitzgerald Haney | 1991 | SFS/MSFS | United States Ambassador to Costa Rica, 2015–17 | |
| Harry B. Harris Jr. | 1994 | SSP | United States Ambassador to South Korea, 2018–2021; former commander, U.S. Pacific Command; U.S. Navy admiral | |
| 1940 | SFS | United States Ambassador to Turkey, 1965–68; United States Ambassador to Saudi Arabia, 1961–65; United States Ambassador to Kuwait, 1962–63; United States Ambassador to Yemen, 1961–62 | |
| 1981 | SFS | President and CEO of International Centre for Missing & Exploited Children; Assistant Secretary of State for Consular Affairs, 2002–08; United States Ambassador to Paraguay, 1997–99 | |
| 1974 | SFS | United States Ambassador to Ukraine, 2003–06; United States Ambassador to Uzbekistan, 2000–03 | |
| 1988 | SFS | President and CEO of Meridian International Center, 2006–present; United States Ambassador to the United Nations for Special Political Affairs, 2003–05; Principal Deputy Assistant Secretary of State for Public Affairs and coordinator of the Bureau of International Information Programs, 2001–03; Special Assistant to the President and associate director of Presidential Personnel, 2001–03 | |
| 1982 | SFS | United States Ambassador to Thailand, 2007–10 | |
| 1932 | SFS | United States Ambassador-at-Large, 1973–77; United States Ambassador to Japan, 1966–68; United States Ambassador to Thailand, 1958–61; United States Ambassador to Czechoslovakia, 1953–57 | |
| 1964 | Law | United States Ambassador to Mexico, 1993–97; member of the U.S. House of Representatives from Oklahoma, 1973–87; White House Appointments Secretary, 1968–69 | |
| 1982 | SFS Fellow | United States Ambassador to Finland, 1991–94; Assistant Secretary of State for Near Eastern and South Asian Affairs, 1989–91; United States Ambassador to Lebanon, 1986–88 | |
| 1948, 1950 | Grad, Grad | United States Ambassador to Thailand, 1973–75; member of the board of directors, United States Institute of Peace | |
| 1960 | SFS | United States Ambassador to Mongolia, 1997–2000 | |
| 1979, 1985 | SFS, Grad | Undersecretary of Commerce for International Trade, 2005–07; United States Ambassador to Singapore, 2001–05 | |
| 1924, 1925 | SFS, Grad | United States Ambassador to Israel, 1954–59; United States Ambassador to Iceland, 1949–54 | |
| 1977 | SFS | United States Ambassador to Honduras, 2008–11 | |
| 1961 | SFS | United States Ambassador to the Organization of American States, 2003–07; United States Ambassador to Venezuela, 1997–2000; United States Ambassador to Nicaragua, 1993–96 | |
| 1975 | SFS | Deputy Assistant Secretary of State for European and Canadian Affairs, 1997–99; United States Ambassador to Kyrgyzstan, 1994–97 | |
| 1963 | Col | United States Ambassador to the Organization of American States, 1985–89; Under Secretary of State for Economic, Business, and Agricultural Affairs, 1989–91 | |
| 1978 | SFS | United States Ambassador to Guinea, 2004–07; United States Ambassador to the Gambia, 2001–04 | |
| 1929 | SFS | United States Ambassador to Finland, 1952–55; Assistant Secretary of State for Legislative Affairs, 1949–52 | |
| 1968, 1974 | SFS, Law | United States Ambassador to Portugal, 1997–2001 | |
| 1956 | Law | United States Ambassador to Romania, 1994–97 | |
| 1980 | SFS | Executive Secretary of the U.S. Department of State, 2009–12; Acting Assistant Secretary of State for Political-Military Affairs, 2007–08; United States Ambassador to Poland, 2012–15; United States Ambassador to Lithuania, 2003–06 | |
| 1991 | SFS Rusk Fellow | United States Ambassador to Pakistan, 2010–12; United States Ambassador to Serbia, 2007–09 | |
| 1977 | SFS | United States Ambassador to Libya, 2019–present; United States Ambassador to Georgia, 2012–2015; United States Ambassador to Uzbekistan, 2007–10 | |
| 1950 | SFS | United States Ambassador to Argentina, 1983–86; United States Ambassador to Peru, 1981–83; United States Ambassador to Guatemala, 1979–80; United States Ambassador to Barbados, Grenada, Dominica, St. Lucia, Antigua, St. Christopher-Nevis-Anguilla, 1977–79 | |
| 1978 | Grad | United States Ambassador to Bolivia, 2000–02 | |
| 1975, 1978 | Col, Law | United States Ambassador to the Holy See, 2005–08 | |
| 1978 | Law | United States Ambassador to Lebanon, 1998–2001 | |
| 1978 | LL.M. | First United States Ambassador-at-Large for War Crimes Issues, 1997–2000 | |
| 1968, 1972 | Col, Law | United States Ambassador to Sweden, 1994–98 | |
| 1984 | MSFS | U.S. representative for Special Political Affairs at the United Nations, 1997–2001; chairperson of the Public Interest Declassification Board, 2012–15 | |
| | SFS | United States Ambassador to the Democratic Republic of the Congo, 2013–2016; United States Ambassador to Djibouti, 2008–11 | |
| 1978 | Grad | United States Ambassador to Russia, 2014–2017; United States Ambassador to Ukraine, 2009–13; United States Ambassador to Georgia, 2005–09; United States Ambassador to Lithuania, 2000–03 | |
| 1963 | SFS | United States Ambassador to Qatar, 1995–98 | |
| 1947 | SFS | Assistant Secretary of State for Inter-American Affairs, 1978–79; United States Ambassador to Venezuela, 1976–78; United States Ambassador to Colombia, 1974–76; United States Ambassador to Costa Rica, 1972–74 | |
| 1998 | Law | United States Ambassador to India, 2015–2017; Assistant Secretary of State for Legislative Affairs, 2009–present | |
| 1966, 1969 | SLL, Grad | United States Ambassador-at-Large for Global Women's Issues; Assistant to President Bill Clinton and Chief of Staff to First Lady Hillary Clinton, 1997–2001; co-founder and chair of Vital Voices Global Partnership | |
| 1949 | SFS | Director of the Bureau for Refugee Programs, 1982; United States Ambassador to Switzerland, 1979–81 | |
| 1975 | SFS | Assistant Secretary of State for Near Eastern Affairs, 2005–08; United States Ambassador to Egypt, 2001–05; Assistant Secretary of State for International Organization Affairs, 1998–2002 | |
| 1956 | SFS | United States Ambassador to Estonia, 1998–2001; United States Ambassador to Congo-Kinshasa, 1991–93; United States Ambassador to Mozambique, 1987–90; United States Ambassador to Guinea-Bissau, 1976–77; United States Ambassador to Cape Verde, 1976–77 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1974, 1978 | Col, Med | United States senator from Wyoming, 2007–present | |
| 1934 | Law | United States senator from Nevada, 1954–74 | |
| 1920 | Law | United States senator from New Mexico, 1935–62; first American-born Hispanic senator; member of the United States House of Representatives, 1931–35 | |
| 1966, 1969 | SFS, Law | Senate majority whip, 2007–15; Senate minority whip, 2015–present; United States senator from Illinois, 1997–present; member of the United States House of Representatives, 1983–97 | |
| 1965 | Law | United States senator from New Hampshire, 1975–80 | |
| 1934 | Col | United States senator from Michigan, 1959–76; Lieutenant Governor of Michigan, 1955–59; Hart Senate Office Building named in his honor | |
| 1978 | Law | United States senator from Hawaii, 2013–present; member of the United States House of Representatives, 2007–13; lieutenant governor of Hawaii, 1994–2002 | |
| 1836 | Col | United States senator from New York, 1875–81; member of the United States House of Representatives, 1863–65 | |
| 1992 | Law | United States senator from Illinois, 2010–17; member of the United States House of Representatives, 2001–10 | |
| 1908 | Law | United States senator from Rhode Island, 1949–50 | |
| 1964 | Law | United States senator from Vermont, 1975–2023; president pro tempore of the United States Senate, 2012–15 | |
| 1994 | Law | United States senator from Florida, 2009–11 | |
| 1869 | Col | United States senator from Florida, 1897–1907; member of the United States House of Representatives, 1891–95 | |
| | | United States senator from Maryland, 1838–45 | |
| 1961 | Law | United States senator from Maine, 1980–95; Senate majority leader, 1989–95; deputy president pro tempore of the United States Senate, 1987–89; judge, United States District Court for the District of Maine, 1979–80; U.S. special envoy for Northern Ireland, 1995–2001; chancellor of the Queen's University, Belfast, 1999–2009; U.S. special envoy for Middle East Peace, 2009–11; chairman of the Disney Company, 2004–07 | |
| 1938 | Law | United States senator from New Mexico, 1964–77; member of the United States House of Representatives, 1957–64; lieutenant governor of New Mexico, 1955–57, 1947–51 | |
| 1980 | Col | United States senator from Alaska, 2002–present | |
| 1920 | Law | United States Senator from Wyoming, 1934–53 | |
| 2009 | SFS | United States senator from Georgia, 2021–present | |
| | Col | United States senator from North Dakota, 1893–99 | |
| 1993, 1993 | MSFS, Law | United States senator from Alaska, 2015–present; attorney general of Alaska, 2009–10; Assistant Secretary of State for Economic and Business Affairs, 2006–09 | |
| 1990 | Law | United States senator from Maryland, 2017–present; chairman of the Democratic Senatorial Campaign Committee, 2017–2019; United States representative from Maryland, 2003–2017; chairman of the Democratic Congressional Campaign Committee, 2007–11 | |
| 1975 | Law | United States senator from Virginia, 2007–13; U.S. Secretary of the Navy, 1987–88 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1932 | Col | United States representative from Missouri, 1947–49, 1951–53 | |
| 1895 | Law | Speaker of the United States House of Representatives, 1936–40; United States representative from Alabama, 1917–40 | |
| 1977 | Law | United States representative from Georgia, 1995–2003 | |
| 1894 | Law | United States representative from Nevada, 1907–11 | |
| 1956 | Law | United States representative from Virginia, 1983–2000 | |
| 1959 | SFS | United States representative from Maryland, 1973–81 | |
| 1952 | Col | United States representative from Virginia, 1981–2001 | |
| 1971 | Law | United States representative from New York, 1977–79 | |
| 1991 | Law | United States representative from Louisiana, 2008–09 | |
| 1986 | Law | United States representative from Rhode Island, 2011–23 | |
| 1987 | Law | United States representative from Michigan, 2011–13 | |
| 1914 | Law | United States representative from Massachusetts, 1937–49 | |
| 1931 | Law | United States representative from New York, 1949–53 | |
| 1974 | SFS | United States representative from Texas, 2005–present | |
| 1918 | Law | United States representative from California, 1931–33 | |
| 1988 | Law | United States representative from Maryland, 2013–2019; co-founder and CEO of CapitalSource | |
| 2013 | Law | United States representative from Pennsylvania, 2023–present | |
| 1892 | Col | United States representative from Ohio, 1907–1913 | |
| 1975, 1998 | SFS, SCE | United States representative from Michigan, 2015–present; president of the General Motors Foundation | |
| 1949, 1952 | Col, Law | Dean of the United States House of Representatives, 1995–2015; United States representative from Michigan, 1965–2015; longest serving House member in history | |
| 1895 | Law | United States representative from Ohio, 1888–95 | |
| 1896 | Law | United States representative from Massachusetts, 1925–35 | |
| 1949, 1951 | Law, LL.M. | United States representative from Massachusetts, 1971–81; first Roman Catholic Jesuit priest to serve as a voting Member of Congress; Georgetown Law professor | |
| 1901 | Col | United States representative from New York, 1935–37 | |
| 1947 | Law | United States representative from Oklahoma, 1953–73 | |
| 1947 | Law | United States representative from Virginia, 1849–61 | |
| 1978 | Law | United States representative from Illinois, 1983–2007 | |
| 1822 | Col | United States representative from Virginia, 1851–59; United States representative from West Virginia, 1875–77; United States minister to France, 1860–61 | |
| 1995 | MPP | United States representative from New Jersey, 2001–09 | |
| 1947 | Law | United States representative from Maryland, 1959–61 | |
| 1923 | Law | United States representative from Connecticut, 1947–49 | |
| 1986 | MPP | United States representative from Nebraska, 2005–22 | |
| 1973 | Law | United States representative from Florida, 2013–present | |
| 1970 | Law | United States representative from Texas, 1979–2005; president of America Votes | |
| 2013, 2015 | SSP, Grad | United States representative from Wisconsin, 2017–24 | |
| 1998 | SSP | United States representative from California, 2020–2025 | |
| * | Col | United States representative from North Carolina, 1813–16; Georgetown College's first student; Gaston Hall is named after him; helped secure Georgetown University's federal charter | |
| 1921–1922* | Col | United States representative from New Jersey, 1957–65 | |
| 1895 | Law | United States representative from Illinois, 1913–15 | |
| 1920 | Law | United States representative from New York, 1939–52; chairman of the Republican National Committee, 1953–57 | |
| 1917 | Law | United States representative from Indiana, 1939–49; Sergeant at Arms of the United States Senate, 1953–55 | |
| 1951 | Law | United States representative from Virginia, 1975–81 | |
| 1926 | Law | United States representative from Virginia, 1946–63 | |
| 1924 | Law | United States representative from New Jersey, 1935–55 | |
| 1993, 1996, 1997 | Col, Grad, Law | United States representative from South Dakota, 2004–11 | |
| 1949 | Col | United States representative from Maryland, 1969–75 | |
| 2014 | MPP | United States representative from Indiana, 2017–23 | |
| 1966 | Law | United States representative from Maryland, 1981–present; chairman of the House Democratic Caucus, 1989–95; House majority leader, 2007–2011, 2019–2023; House minority whip, 2003–07, 2011–2019 | |
| 1947 | Col | United States representative from Illinois, 1975–2007 | |
| 1908 | Law | United States representative from Illinois, 1935; judge of the United States District Court for the Northern District of Illinois, 1939–65 | |
| 1986 | Col | United States representative from Washington, 2017–present | |
| 1996 | Law | United States representative from Louisiana, 1991–09; convicted of ten corruption charges | |
| 1994 | SPP | United States representative from New York, 2013–present; House minority leader, 2023–present | |
| * | | United States representative from Rhode Island, 1995–2011; chairman of the Democratic Congressional Campaign Committee, 1999–2001; son of Ted Kennedy | |
| 1922 | Law | United States representative from Texas, 1939–61; judge of the United States Court of Military Appeals, 1961–68 | |
| 1984 | Law | United States representative from New Hampshire, 2013–present | |
| 1895 | Law | United States representative from Kentucky, 1903–13 | |
| | Law | United States representative from South Carolina, 1903–13 | |
| 1901 | Law | United States representative from South Carolina, 1901–19 | |
| 1994 | Law | United States representative from California, 2015–present | |
| 1971 | Law | United States representative from California, 2005–13 | |
| 1906, 1909 | Col, Law | United States representative from Maryland, 1915–24 | |
| 2004 | MSFS | United States representative from Florida, 2017–23 | |
| 1969 | Dent | United States representative from Georgia, 1995–2007 | |
| 1996 | SFS | United States representative from Virginia, 2009–11 | |
| 1934 | Col | United States representative from Montana, 1937–39 | |
| 1909 | Col | United States representative from Connecticut, 1923–25 | |
| 1933 | Col | United States representative from Connecticut, 1947–59 | |
| 2019 | MSB | United States representative from Texas, 2021–present | |
| 1988 | SFS | United States Delegate from the United States Virgin Islands, 2015–present | |
| 1959 | Law | United States representative from Connecticut, 1979–85 | |
| 1904 | Law | United States representative from Pennsylvania, 1911–13 | |
| 1922 | Law | United States representative from Rhode Island, 1935–37, 1939–41 | |
| 1953 | Law | United States representative from New York, 1973–75 | |
| 2013 | SSP | United States representative from New York, 2022–present | |
| 1931 | Law | United States representative from Connecticut, 1947–59 | |
| 1996 | Law | United States representative from Kansas, 2015–present; attorney general of Kansas, 2011–2023 | |
| 2005 | Col | United States representative from New York, 2022–23 | |
| 1964 | SFS | United States representative from Indiana, 1975–95; president of Resources for the Future, 2005–present | |
| 2007 | Law | United States representative from New Jersey, 2019–present | |
| 1949 | SFS | United States representative from Ohio, 1965–83 | |
| 2003 | MSB | United States representative from Wisconsin, 2019–present | |
| 1916 | Law | United States representative from Ohio, 1933–39, 1941–43, 1945–47 | |
| 1995 | SFS | United States representative from Massachusetts, 2019–present | |
| 1893 | Law | United States representative from Nevada, 1903–07 | |
| 1982 | Law | United States representative from Indiana, 1985–2023 | |
| 1873 | Col | United States delegate from the Washington Territory, 1885–89 | |
| 1980 | Law | United States representative from Washington, 1995–99 | |
| 1965 | Law | United States representative from Virginia, 1981–2015 | |
| 1977 | Law | United States representative from Maryland, 1993–2008 | |
| Name | Class year | School/ degree | Notability | Reference |
| 1989 | Law | President of HBO miniseries and Academy Award-winning documentary filmmaker | |
| 1985 | Col | Singer and actress; winner of the Tony Award, Daytime Emmy Award, and Screen Actors Guild Life Achievement Award; recipient of the Presidential Medal of Freedom | |
| 1895–1897* | Col | Actor | |
| 2001 | Col | Director and screenwriter | |
| 1970 | SFS | Franco-Tunisian film producer | |
| 2004 | Col | Actor | |
| 1978 | Law | Chairman and CEO of Village Roadshow Pictures | |
| Sometime 1950s | Col | Actress known for Private Benjamin, for which she received an Academy Award nomination | |
| 2005 | Col | Director and screenwriter | |
| 1997 | Col | Filmmaker with 12 Academy Award nominations as an actor, writer, and producer; winner of 3 Grammy Awards; nominated for a Tony Award and 6 Golden Globes | |
| 1995 | Col | Producer of Grey Gardens; winner of an Emmy Award, a Golden Globe Award, and a TCA Award | |
| 1992 | Grad | Pulitzer Prize-winning playwright known for Wit | |
| c. 1963 | | Child actor, portrayed the kidnap victim in "Fearful Decision" and Tom Sawyer to Eileen Heckart's Aunt Polly in an episode of Campbell Television Playhouse | |
| 1993 | Law | Actor | |
| | Col | Independent filmmaker | |
| 1960 | Col | Five-time Tony Award-winning playwright known for The House of Blue Leaves, Six Degrees of Separation, and Landscape of the Body | |
| 1971 | Col | Tony Award-winning director known for The Elephant Man play on Broadway | |
| 1985 | Col | Television writer and producer; creator of Arrested Development; co-creator of The Ellen Show | |
| 2001 | Col | Actor and comedian known for his role in The League and starring in the Kroll Show | |
| 1914 | Grad | Early stage and film actor; first portrayed the character of Svengali | |
| 1992 | Col | Director known for Undercover Brother and The Best Man | |
| 1889 | Col | Canadian actor, director, and playwright | |
| 2005 | Col | Actress and screenwriter | |
| 1984 | Law | Star and judge of The People's Court; former Florida circuit court judge | |
| Andrew Morrison | 2015 | Col | Academy Award-nominated producer, winner of the Golden Globe Award for Best Motion Picture – Drama for The Brutalist | |
| 1984 | MSB | Producer known for Transformers, Transformers: Revenge of the Fallen, and Natural Born Killers | |
| 1992 | SFS | Documentary director known for Smile Pinki; winner of the Academy Award for Best Short Subject Documentary | |
| 1999 | Col | Academy Award-nominated screenwriter for Memento; co-wrote Interstellar and The Dark Knight; creator of Westworld | |
| 1943 | SFS | Actor, director, writer, and producer; winner of nine Emmy Awards and one Grammy Award | |
| 2012 | Col | Actress | |
| RaMell Ross | 2005 | Col | Director and co-writer of Nickel Boys, nominated for the Academy Award for Best Adapted Screenplay | |
| 1995 | SFS | Golden Globe Award and Emmy Award-winning director and writer known for Grey Gardens | |
| 1989 | Col | Actor | |
| 1987 | | Director known for four Harry Potter films | |
| 1989 | Col | Former talk show host on KFI; documentary writer and director | |