List of Coronavirus live isolates


This article aims at keeping an up-to-date list of Coronavirus strains and subspecies successfully isolated and cultured in laboratory, a task which is often challenging. When relevant it shall include a few synthetic chimera as well as some strains that were only propagated in laboratory animals.

Alphacoronavirus

  • 229E
  • NL63
  • GX P2V
  • PEDV, propagated in piglets, repeated passage in Vero cells, using Vero/TMPRSS2 and Vero/MSPL cells
  • SADS

Tegacovirus

Betacoronavirus

Merbecovirus

  • HKU5 SARS-S chimera
  • HKU5 and a MERS PDF-2180-S chimera, with trypsin
  • Various MERS HKU4-RBD chimera
  • HKU4
  • MERS
  • HKU4-like Pangolin Coronavirus

Embecovirus

Sarbecovirus

  • SARS
  • HKU3 SARS-RBD synthetic recombinant
  • bat-SL-CoV ZC45
  • WIV1
  • RsSHC014
  • WIV16
  • WIV1 Rs4874-S synthetic chimera
  • Rs4874 and two synthetic chimera WIV1 Rs7237-S and WIV1 Rs4231-S
  • SARS-CoV-2
  • BANAL-236
  • Pangolin Guangxi P2V
  • Rco319, Rc-os20, Rc-mk2, Rc-kw8
  • WIV1 Rs4081-S synthetic chimera. In the spike it is a member of clade 2.
  • WIV1 RsSHC014-S1 chimera
  • Two clade 1 viruses RsYN2012 and RsYN2016 and one clade 2 virus RsHuB2019 in Huh7 cells with trypsin.
  • pangolin/Guangdong, in Vero cells, human organoids, hACE2 mice, hamsters

Gammacoronavirus

Deltacoronavirus