List of American films of 2010
This is a list of American films released in 2010.
Box office
The highest-grossing American films released in 2010, by domestic box office gross revenue, are as follows:| Rank | Title | Distributor | Domestic gross |
| 1 | Toy Story 3 | Disney | $415,004,880 |
| 2 | Alice in Wonderland | Disney | $334,191,110 |
| 3 | Iron Man 2 | Paramount | $312,433,331 |
| 4 | The Twilight Saga: Eclipse | Summit | $300,531,751 |
| 5 | Harry Potter and the Deathly Hallows – Part 1 | Warner Bros. | $295,983,305 |
| 6 | Inception | Warner Bros. | $292,576,195 |
| 7 | Despicable Me | Universal | $251,513,985 |
| 8 | Shrek Forever After | Paramount | $238,736,787 |
| 9 | How to Train Your Dragon | Paramount | $217,581,231 |
| 10 | Tangled | Disney | $200,821,936 |