List of American films of 1988
This is a list of American films released in 1988.
Box office
The highest-grossing American films released in 1988, by domestic box office gross revenue, are as follows:| Rank | Title | Distributor | Domestic gross |
| 1 | Rain Man | MGM | $172,825,435 |
| 2 | Who Framed Roger Rabbit | Buena Vista | $156,452,370 |
| 3 | Coming to America | Paramount | $128,152,301 |
| 4 | Big | 20th Century Fox | $114,968,774 |
| 5 | Twins | Universal | $111,938,388 |
| 6 | Crocodile Dundee II | Paramount | $109,306,210 |
| 7 | Die Hard | 20th Century Fox | $83,008,852 |
| 8 | The Naked Gun: From the Files of Police Squad! | Paramount | $78,756,177 |
| 9 | Cocktail | Buena Vista | $78,222,753 |
| 10 | Beetlejuice | Geffen | $73,707,461 |