| Chapter | Charter date and range | Institution | Location | Status | |
| Alpha of Illinois | | University of Illinois College of Medicine | Chicago, Illinois | Active | |
| Beta of Illinois | | Pritzker School of Medicine | Chicago, Illinois | Active | |
| Gamma of Illinois | | Feinberg School of Medicine | Evanston, Illinois | Active | |
| Alpha of Ohio | | Case Western Reserve University School of Medicine | Cleveland, Ohio | Active | |
| Alpha of Pennsylvania | | Sidney Kimmel Medical College | Philadelphia, Pennsylvania | Active | |
| Beta of Pennsylvania | | Perelman School of Medicine | Philadelphia, Pennsylvania | Active | |
| Alpha of Missouri | | Washington University School of Medicine | St. Louis, Missouri | Active | |
| Alpha of Massachusetts | | Harvard Medical School | Boston, Massachusetts | Inactive | |
| Alpha of California | | UCSF School of Medicine | San Francisco, California | Inactive | |
| Alpha of Maryland | | Johns Hopkins School of Medicine | Baltimore, Maryland | Active | |
| Alpha of Ontario | | University of Toronto Faculty of Medicine | Toronto, Ontario | Active | |
| Alpha of New York | | Columbia University College of Physicians and Surgeons | Manhattan, New York City, New York | Active | |
| Alpha of Michigan | | University of Michigan Medicine | Ann Arbor, Michigan | Active | |
| Alpha of Minnesota | | University of Minnesota Medical School | Minneapolis, Minnesota | Active | |
| Beta of New York | | Weill Cornell Medicine | New York City, New York | Active | |
| Gamma of New York | | State University of New York Upstate Medical University | Syracuse, New York | Active | |
| Alpha of Quebec | | McGill University Faculty of Medicine and Health Sciences | Montreal, Quebec, Canada | Inactive | |
| Alpha of Nebraska | | University of Nebraska Medical Center | Omaha, Nebraska | Active | |
| Alpha of Louisiana | | Tulane University School of Medicine | New Orleans, Louisiana | Active | |
| Beta of Ohio | | University of Cincinnati Health | Cincinnati, Ohio | Active | |
| Gamma of Pennsylvania | | University of Pittsburgh School of Medicine | Pittsburgh, Pennsylvania | Active | |
| Alpha of Indiana | | Indiana University School of Medicine | Indianapolis, Indiana | Active | |
| Alpha of Virginia | | University of Virginia School of Medicine | Charlottesville, Virginia | Active | |
| Alpha of Iowa | | Roy J. and Lucille A. Carver College of Medicine | Iowa City, Iowa | Active | |
| Alpha of Texas | | McGovern Medical School | Houston, Texas | Active | |
| Alpha of Connecticut | | Yale School of Medicine | New Haven, Connecticut | Inactive | |
| Alpha of Tennessee | | Vanderbilt University School of Medicine | Nashville, Tennessee | Active | |
| Delta of New York | | New York University Grossman School of Medicine | New York City, New York | Active | |
| Alpha of Oregon | | Oregon Health & Science University | Portland, Oregon | Active | |
| Beta of Missouri | | Saint Louis University School of Medicine | St. Louis, Missouri | Active | |
| Epsilon of New York | | Jacobs School of Medicine and Biomedical Sciences | Buffalo, New York | Active | |
| Alpha of Kentucky | | University of Louisville School of Medicine | Louisville, Kentucky | Active | |
| Alpha of Colorado | | University of Colorado School of Medicine | Aurora, Colorado | Active | |
| Alpha of Wisconsin | | University of Wisconsin School of Medicine and Public Health | Madison, Wisconsin | Active | |
| Alpha of Georgia | | Medical College of Georgia | Augusta, Georgia | Active | |
| Beta of California | | Stanford University School of Medicine | Stanford, California | Active | |
| Zeta of New York | | University of Rochester School of Medicine and Dentistry | Rochester, New York | Active | |
| Alpha of Kansas | | University of Kansas School of Medicine | Kansas City, Kansas | Active | |
| Alpha of North Carolina | | Duke University School of Medicine | Durham, North Carolina | Active | |
| Gamma of Ohio | | Ohio State University College of Medicine | Columbus, Ohio | Active | |
| Delta of Pennsylvania | | Woman's Medical College of Pennsylvania | Philadelphia, Pennsylvania | Inactive | |
| Beta of Georgia | | Emory University School of Medicine | Atlanta, Georgia | Active | |
| Beta of Massachusetts | | Tufts University School of Medicine | Boston, Massachusetts | Active | |
| Beta of Virginia | | VCU Medical Center | Richmond, Virginia | Active | |
| Beta of Tennessee | | University of Tennessee Health Science Center | Memphis, Tennessee | Active | |
| Beta of Ontario | | University of Western Ontario | London, Ontario | Inactive | |
| Beta of Michigan | | Wayne State University School of Medicine | Detroit, Michigan | Active | |
| Gamma of Massachusetts | | Boston University School of Medicine | Boston, Massachusetts | Active | |
| Eta of New York | | SUNY Downstate Health Sciences University | New York City, New York | Active | |
| Beta of North Carolina | | Wake Forest School of Medicine | Winston-Salem, North Carolina | Active | |
| Beta of Wisconsin | | Marquette University College of Health Sciences | Milwaukee, Wisconsin | Inactive | |
| Beta of Louisiana | | LSU Health Sciences Center New Orleans | New Orleans, Louisiana | Active | |
| Alpha of Utah | | University of Utah School of Medicine | Salt Lake City, Utah | Active | |
| Gamma of California | | Keck School of Medicine of USC | Los Angeles, California | Active | |
| Beta of Texas | | Baylor University Medical Center | Waco, Texas | Active | |
| Beta of Maryland | | University of Maryland School of Medicine | Baltimore, Maryland | Active | |
| Theta of New York | | Albany Medical College | Albany, New York | Active | |
| Alpha of Alabama | | University of Alabama at Birmingham School of Medicine | Birmingham, Alabama | Active | |
| Alpha of Washington | | University of Washington School of Medicine | Seattle, Washington | Active | |
| Gamma of Texas | | University of Texas Southwestern Medical Center | Dallas, Texas | Active | |
| Epsilon of Pennsylvania | | Temple University School of Medicine | Philadelphia, Pennsylvania | Active | |
| Zeta of Pennsylvania | | Drexel University College of Medicine | Philadelphia, Pennsylvania | Active | |
| Alpha of Vermont | | Robert Larner College of Medicine | Burlington, Vermont | Active | |
| Alpha of South Carolina | | Medical University of South Carolina | Charleston, South Carolina | Active | |
| Alpha of Oklahoma | | University of Oklahoma College of Medicine | Oklahoma City, Oklahoma | Active | |
| Gamma of North Carolina | | UNC School of Medicine | Chapel Hill, North Carolina | Active | |
| Alpha of District of Columbia | | George Washington University School of Medicine & Health Sciences | Washington, D.C. | Active | |
| Beta of District of Columbia | | Georgetown University School of Medicine | Washington, D.C. | Active | |
| Alpha of British Columbia | | UBC Faculty of Medicine | Vancouver, British Columbia, Canada | Inactive | |
| Gamma of District of Columbia | | Howard University College of Medicine | Washington, D.C. | Active | |
| Alpha of Arkansas | | University of Arkansas for Medical Sciences | Little Rock, Arkansas | Active | |
| Delta of California | | David Geffen School of Medicine at UCLA | Los Angeles, California | Active | |
| Alpha of Puerto Rico | | University of Puerto Rico School of Medicine | San Juan, Puerto Rico | Active | |
| Epsilon of California | 1957 | Loma Linda University School of Medicine | Loma Linda, California | Active | |
| Beta of Nebraska | 1957 | Creighton University School of Medicine | Omaha, Nebraska | Active | |
| Iota of New York | 1957 | New York Medical College | Valhalla, New York | Active | |
| Alpha of Mississippi | 1957 | University of Mississippi School of Medicine | Oxford, Mississippi | Active | |
| Gamma of Tennessee | 1957 | Meharry Medical College | Nashville, Tennessee | Active | |
| Gamma of Missouri | 1957 | University of Missouri School of Medicine | Columbia, Missouri | Active | |
| Alpha of Lebanon | 1958 | American University of Beirut Faculty of Medicine | Beirut, Lebanon | Active | |
| Alpha of Nova Scotia | 1958 | Dalhousie University Faculty of Medicine | Halifax, Nova Scotia, Canada | Inactive | |
| Alpha of Alberta | 1958 | University of Alberta Faculty of Medicine and Dentistry | Edmonton, Alberta, Canada | Inactive | |
| Alpha of Florida | 1959 | Miller School of Medicine | Miami, Florida | Active | |
| Kappa of New York | 1959 | Albert Einstein College of Medicine | New York City, New York | Active | |
| Beta of Florida | 1960 | University of Florida College of Medicine | Gainesville, Florida | Active | |
| Alpha of West Virginia | 1962 | West Virginia University School of Medicine | Morgantown, West Virginia | Active | |
| Alpha of New Mexico | 1968 | University of New Mexico School of Medicine | Albuquerque, New Mexico | Active | |
| Gamma of Louisiana | 1973 | LSU Health Sciences Center Shreveport | Shreveport, Louisiana | Active | |
| Zeta of Texas | 1974 | Texas Tech University Health Sciences Center School of Medicine | Lubbock, Texas | Active | |
| Delta of Ohio | 1974 | University of Toledo College of Medicine and Life Sciences | Toledo, Ohio | Active | |
| Alpha of South Dakota | 1978 | University of South Dakota Sanford School of Medicine | Vermillion, Sioux Falls, Rapid City, and Yankton, South Carolina | Active | |
| Zeta of Ohio | 1982 | Northeast Ohio Medical University | Rootstown, Ohio | Active | |
| Delta of Tennessee | 1985 | East Tennessee State University James H. Quillen College of Medicine | Johnson City, Tennessee | Active | |
| 1985 | University of Nevada, Reno School of Medicine | Reno, Nevada | Active | |
| Gamma of Georgia | 1989 | Morehouse School of Medicine | Atlanta, Georgia | Active | |
| Beta of Puerto RIco | 1990 | Ponce Health Sciences University | Ponce, Puerto Rico | Active | |
| Alpha of Hawaii | 1990 | John A. Burns School of Medicine | Honolulu, Hawaii | Active | |
| Delta of Massachusetts | 1996 | UMass Chan Medical School | Worcester, Massachusetts | Active | |
| Gamma of Puerto Rico | 1990–2020 | Universidad Central del Caribe | Bayamón, Puerto Rico | Active | |
| Delta of Michigan | 2011 | Oakland University William Beaumont School of Medicine | Auburn Hills, Michigan | Active | |
| Epsilon of Florida | 2012 | FIU Herbert Wertheim College of Medicine | Miami-Dade County, Florida | Active | |
| 2012 | Boonshoft School of Medicine | Dayton, Ohio | Active | |
| 2014 | Geisinger Commonwealth School of Medicine | Pennsylvania | Active | |
| Nu of New York | 2015 | Zucker School of Medicine | Hempstead, New York | Active | |
| Beta of Connecticut | 2016 | University of Connecticut School of Medicine | Farmington, Connecticut | Active | |
| Gamma of New Jersey | | Cooper Medical School of Rowan University | Camden, New Jersey | Active | |
| Delta of Puerto Rico | | San Juan Bautista School of Medicine | Caguas, Puerto Rico | Active | |
| Zeta of Michigan | 2021 | Central Michigan University College of Medicine | Mount Pleasant, Michigan | Active | |
| | UNLV School of Medicine | Paradise, Nevada | Active | |
| Epsilon of Illinois | 2022 | Stritch School of Medicine | Chicago, Illinois | Active | |
| Xi of New York | | CUNY School of Medicine | Manhattan, New York City, New York | Active | |
| Beta of Arizona | 2024 | University of Arizona College of Medicine – Phoenix | Phoenix, Arizona | Active | |
| | Geisel School of Medicine | Hanover, New Hampshire | Active | |
| | ECU Brody School of Medicine | Greenville, North Carolina | Active | |
| | Eastern Virginia Medical School | Norfolk, Virginia | Active | |
| | Charles E. Schmidt College of Medicine | Boca Raton, Florida | Active | |
| | Florida State University College of Medicine | Tallahassee, Florida | Active | |
| | Icahn School of Medicine at Mount Sinai | New York City, New York | Active | |
| | Joan C. Edwards School of Medicine | Huntington, West Virginia | Active | |
| | Medical College of Wisconsin | Milwaukee, Wisconsin | Active | |
| | Mercer University School of Medicine | Macon, Georgia | Active | |
| Gamma of Michigan | | Michigan State University College of Human Medicine | East Lansing, Michigan | Active | |
| Theta of Florida | | Dr. Kiran C. Patel College of Allopathic Medicine | Davie, Florida | Active | |
| | Penn State University College of Medicine | Hershey, Pennsylvania | Active | |
| | Renaissance School of Medicine at Stony Brook University | Stony Brook, New York | Active | |
| | Robert Wood Johnson Medical School | New Brunswick, New Jersey | Active | |
| | Rosalind Franklin University of Medicine and Science | North Chicago, Illinois | Active | |
| | Rush Medical College | Chicago, Illinois | Active | |
| Beta of New Jersey | | New Jersey Medical School | Newark, New Jersey | Active | |
| Eta of Illinois | | Southern Illinois University School of Medicine | Springfield, Illinois | Active | |
| | Texas A&M School of Medicine | Bryan, Texas | Active | |
| | Paul L. Foster School of Medicine | El Paso, Texas | Active | |
| Gamma of Maryland | | Uniformed Services University of the Health Sciences | Bethesda, Maryland | Active | |
| | University of Arizona College of Medicine – Tucson | Tucson, Arizona | Active | |
| | UC Davis School of Medicine | Davis, California | Active | |
| | University of California, Irvine School of Medicine | Irvine, California | Active | |
| Zeta of Florida | | University of Central Florida College of Medicine | Orlando, Florida | Active | |
| | University of Kentucky College of Medicine | Lexington, Kentucky | Active | |
| | University of Missouri–Kansas City School of Medicine | Kansas City, Missouri | Active | |
| | University of North Dakota School of Medicine and Health Sciences | Grand Forks, North Dakota | Active | |
| Beta of Alabama | | Frederick P. Whiddon College of Medicine | Mobile, Alabama | Active | |
| | School of Medicine Columbia | Columbia, South Carolina | Active | |
| | School of Medicine Greenville | Greenville, South Carolina | Active | |
| Gamma of Florida | | University of South Florida College of Medicine | Tampa, Florida | Active | |
| | Dell Medical School | Austin, Texas | Active | |
| | Long School of Medicine | San Antonio, Texas | Active | |
| | University of Texas Medical Branch | Galveston, Texas | Active | |
| | Virginia Tech Carilion School of Medicine and Research Institute | Roanoke, Virginia | Active | |
| | Alpert Medical School | Providence, Rhode Island | Active | |
| Epsilon of Michigan | | Western Michigan University Homer Stryker M.D. School of Medicine | Kalamazoo, Michigan | Active | |