Limits of Neutral Drift: Lessons From the In Vitro Evolution of Two Ribozymes
Limits of Neutral Drift: Lessons From the In Vitro Evolution of Two Ribozymes is a scholarly work by Katherine L Petrie, published in 2014 in ''Journal of Molecular Evolution''. The main subjects of the publication include evolutionary dynamics, CRISPR, fitness, genetic variation, evolutionary biology, adaptation, biological sequence, genetic drift, ribosome, biology, neutral theory of molecular evolution, genetics, Neutral network, experimental evolution, neutral mutation, glossary of archaeology, fitness landscape, ribozyme, molecular evolution, rate of evolution, selection (genetic algorithm), and sequence space. This is consistent with a fitness landscape where high-fitness genotypes are sparse and well isolated, and suggests, at least in this context, that neutral drift alone is not a primary driver of genetic change.