Lewis and Clark Bridge
- Clark County, Indiana
- Clatsop County, Oregon
- Columbia River
- Interstate 70 in Missouri
- Kansas River
- Lewis and Clark (disambiguation)
- Lewis and Clark Bridge (Columbia River)
- Lewis and Clark Bridge (Ohio River)
- Lewis and Clark Bridge (Wolf Point, Montana)
- Lewis and Clark Expedition
- Lewis and Clark River
- Lewis and Clark River Bridge
- Lewis and Clark Viaduct
- Louisville, Kentucky
- Meriwether Lewis
- Missouri
- Missouri River
- Oregon
- Washington (state)
- William Clark