John Leighton

• John Leighton (MP), MP for Bedford
• John Leighton (artist), artist and book cover designer
• John S. Leighton, politician from New Brunswick
• John Leighton (baseball), Major League Baseball outfielder
• John Leighton (footballer), Nottingham Forest and England footballer
• John Leighton (curator) British art historian, curator and museum director
• John Leighton (miller), a flour miller in early Sydney; his nickname, 'Jack the Miller', is the origin of the name of the suburb of Millers Point.