Leffingwell
- Albert Leffingwell (novelist)
- Albert Leffingwell (physician)
- Charles Wesley Leffingwell
- Douglas Leffingwell
- Edward Leffingwell
- Ernest de Koven Leffingwell
- Frank Seth Leffingwell
- Lee Leffingwell
- Leffingwell Camp Site
- Leffingwell Inn
- Orwell Township, Ashtabula County, Ohio
- Russell Cornell Leffingwell
- William Henry Leffingwell
- William Leffingwell (Iowa politician)
- William Leffingwell (New York politician)