Latin American Music Awards of 2021
The 6th Annual Latin American Music Awards were held at the BB&T Center in Sunrise, Florida. It was broadcast live on Telemundo. J Balvin and Karol G led the nominations, with nine nods each.
Presenters
;Premiere ceremony- Ana Bárbara
- Carlos Adyan
- Jorge Bernal
- Rodner Figueroa
- Vadhir Derbez
- Zuleyka Rivera
- Andrea Balsa
- Ariadna Gutiérrez
- Alex Fernández
- Arthur Hanlon
- Alex Rose
- Adamari López
- Christian Chávez
- Chayanne
- Chesca
- Danilo Carrera
- Danny Feliz
- Emilia
- Fonseca
- Gaby Espino
- Goyo
- Jaqueline Bracamontes
- Jesús Moré
- Jessi Uribe
- Marc Anthony
- Maribel Guardia
- Ninel Conde
- Prince Royce
- Seven Kayne
- William Levy
- Zozibini Tunzi
Winners and nominees
The nominations were announced on March 2, 2021.Multiple nominations and awards
| Awards | Act |
| 5 | Bad Bunny |
| 3 | Karol G |
| 3 | Nicki Minaj |
| 2 | Christian Nodal |
| 2 | Eslabon Armado |
| 2 | Prince Royce |
Special awards
- Icon Award: Alejandro Fernández
- Legend Award: José Luis Rodríguez 'El Puma'
- Extraordinary Evolution Award: Ozuna