Lambdapapillomavirus


Lambdapapillomavirus is a genus of viruses in the family Papillomaviridae. Cats and dogs serve as natural hosts. There are five species in this genus. Diseases associated with this genus include mucosal and cutaneous lesions.

Taxonomy

The following five species are assigned to the genus:Lambdapapillomavirus 1Lambdapapillomavirus 2Lambdapapillomavirus 3Lambdapapillomavirus 4
  • ''Lambdapapillomavirus 5''

Structure

Viruses in Lambdapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
LambdapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Cats and dogs serve as the natural host. Transmission routes are contact.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
LambdapapillomavirusCats; dogsEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact