LSP
- Josefa Camejo International Airport
- Label-switched path
- Landing Ship
- Language Server Protocol
- Language for specific purposes
- Laser shock peening
- Launch Services Program
- Launch service provider
- Layered Service Provider
- Lego Serious Play
- Liberal State Party
- Lightest Supersymmetric Particle
- Line spectral pairs
- Linguistic Society of the Philippines
- Link state packet
- Liskov substitution principle
- Local strategic partnership
- Localized surface plasmon
- Logistics service provider
- London School of Philosophy
- Louisiana State Penitentiary
- Louisiana State Police
- Lumpy Space Princess
- Lysergic acid 3-pentyl amide
- Oracle Data Guard
- Socialist Party of Latvia
- The Last Shadow Puppets