LCO
- ICO (disambiguation)
- LC0 (disambiguation)
- LCOS
- Lac Courte Oreilles Band of Lake Superior Chippewa Indians
- Lague Airport
- Las Cachorras Orientales
- Las Campanas Observatory
- Las Cumbres Observatory
- League of Legends Circuit Oceania
- Legislative Competence Order
- Libraries Connect Ohio
- List of multiple-system operators
- Lithium cobalt oxide
- Lithuanian Chamber Orchestra
- London Chamber Orchestra
- London Contemporary Orchestra
- Missile combat crew