Kynapcin
Kynapcin is a general name for a number of dibenzofuranyl derivatives of the molecule polyozellin, present in the fungus Polyozellus multiplex. Like polyozellin, some kynapcins inhibit prolyl endopeptidase, an enzyme that has a role in processing proteins including amyloid [precursor protein]. Chemicals that inhibit prolyl endopeptidase have attracted research interest due to their potential therapeutic effects. Several kynapcins have been found in P. multiplex, each with different chemical properties, including kynapcin-12, kynapcin-13 and -28, and -24. A total synthesis of kynapcin-24 was achieved in 2009.