Karla Satchell


Karla Satchell,, is an American microbiologist who is currently the Anne Stewart Youman's Professor of Microbiology at Northwestern University Feinberg School of Medicine and an elected fellow of the American Association for the Advancement of Science. and the American Academy of Microbiology

Education

She earned her Ph.D at University of Washington in 1996 and conducted postdoctoral training with John Mekalanos at Harvard Medical School.

Research

Her interests are microbiology, structural biology, cytoskeleton, cellular microbiology, bacteria and diseases and pathogenesis. She is especially known for defining how the MARTX toxins of Vibrio cholerae and Vibrio vulnificus are modular proteins that deliver their constituent effectors to host cells to modify cell signaling to promote bacterial infection.

Structural Biology

Satchell is head of the Center for Structural Biology of Infectious Diseases at Northwestern since 2017. The Center, established in 2007, provides an established consortium of laboratories in North America for rapid response research related to infectious disease outbreaks. The center determines 3-D structure of proteins from causing infectious such as bacteria, viruses and fungi to probe mechanisms of disease and inform strategies for effective diagnostics, vaccines and treatments.

Publications

Awards and honors