The Dano-Norwegian settlement Sukkertoppen was originally located at the site of present-day Kangaamiut, when it was founded in 1755. It was moved to its present location at Maniitsoq in 1782.
Kangaamiut has experienceda sharp decline in its population. The settlement has lost more than 36% of its population relative to 1990 and more than 26% relative to 2000.