KY 448 begins at KY 313 on the southeast side of Brandenburg. From there, KY 448 turns right and travels to the north-northwest. It passes Brandenburg Primary School and David T. Wilson Elementary School. The highway then passes Meade Olin Park and intersects the northern terminus of KY 710. This intersection is just to the north-northeast of Meade County High School. It curves to the northwest and passes Ramsey Field and intersects the southern terminus of KY 2204. The highway passes the Meade CountyChamber of Commerce and curves to the west-southwest. It intersects the eastern terminus of KY 228 and curves to the southwest. One block later, it intersects the eastern terminus of KY 1692. It passes a U.S. Post Office and the Brandenburg Police Department before it travels just to the west of Meade County High School. It travels through Cap Anderson Cemetery. A short distance later, it meets its northern terminus, an intersection with the northern terminus of KY 79 and KY 313.