KY 109 meets KY 120 and a few other routes in Providence. It continues northwestward into Union County; at Sturgis, it begins a concurrency with U.S. Route 60 for a few miles. It branches off from US 60 to traverse the Henshaw community. KY 109 ends at an intersection with KY 56 a few miles east of the bridge over the Ohio River that marks the Illinois–Kentucky state line near Old Shawneetown, Illinois.