KRT33A


Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I [hair keratin] genes which are clustered in a region of chromosome 17q21.2 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type [II keratin]s to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRT33A and KRT33B.