KCS
- Clinical Centre of Serbia
- Czechoslovak koruna
- Intelligent Platform Management Interface
- KCSF
- Kanawha County Schools
- Kansas City Southern (company)
- Kansas City Southern Railway
- Kansas City standard
- Kennet School
- Keratoconjunctivitis sicca
- Kihei Charter School
- Killed carbon steel
- King's College School
- King's Colour Squadron
- King's Group
- Kingsford Community School
- Knowledge-centered support
- Korean Chemical Society
- Very-long-chain 3-oxoacyl-CoA synthase