José Serrano
José Serrano may refer to:
- José António Serrano, Portuguese physician and anatomist
- José E. Serrano, Member of the U.S. House of Representatives for a portion of The Bronx, New York
- José M. Serrano, his son, New York State Senator
- José Serrano (Ecuadorian politician), Ecuadorian political figure, Minister of the Interior
- José Serrano (composer), Spanish zarzuela composer
- José María Galante Serrano, Spanish activist known as Chato Galante
- José [Mariano Serrano], Bolivian member of the Congress of Tucumán
- José Serrano (footballer, born 1981), Spanish footballer
- Rosso José Serrano, Colombian police officer
- José Serrano (footballer, born 2002), Venezuelan footballer