John Worthington

• John Worthington (academic), English academic and diarist
• John Tolley Hood Worthington, U.S. Representative from Maryland
• John Worthington (British politician), British surgeon, businessman and politician
• John Hubert Worthington, British architect
• John Worthington (architect), professor of architecture at York University
• John Worthington (Neighbours), fictional character on the Australian soap opera ''Neighbours''