John Ryle

• John Ryle (fl. 1414), Member of Parliament for Lincoln in 1414
• John Ryle (politician), Member of Parliament for Macclesfield from 1832 to 1837
• J. C. Ryle, Anglican bishop of Liverpool
• John Ryle (manufacturer), British and American businessman in the silk industry
• John Ryle (professor), British medical professor
• John Ryle (writer), British author and anthropologist