John Roche
John Roche may refer to:
- John A. Roche, Chicago politician
- John Roche , Irish politician
- John Roche , Garda Síochána detective
- John Roche , American actor
- John Roche , retired American professional basketball player
- John Roche , Irishman, one of the English Martyrs executed in 1588, beatified in 1992
- Johnny Roche, English footballer
- Jack Roche, Australian convicted on a charge of conspiring to destroy the Israeli Embassy in Canberra, Australia
- Jack Roche , Major League Baseball catcher
- John Roche , Irish Roman Catholic bishop
- John Francis Roche, American serial killer, burglar, and rapist
- John Roche , member of the Legislative Council of Quebec
- John Roche, appointed in 2025 as the Prime Minister's Chief Science Advisor