John Guise
John Guise may refer to:
- Sir John Guise, 2nd Baronet, English MP for Gloucestershire
- Sir John Guise, 3rd Baronet, English MP for Great Marlow and Gloucestershire
- John Guyse, also spelt Guise, English minister
- John Guise , art collector
- Sir John Guise, 4th Baronet, MP for Aylesbury
- Sir John Guise, 1st Baronet, of the Guise baronets
- Sir John Wright Guise, 3rd Baronet GCB, of the Guise baronets
- John Christopher Guise, British Army officer, Victoria Cross recipient
- John Lindsay Guise, English cricketer
- Sir John Guise, Governor-General of Papua New Guinea
- Sir John Guise, 7th Baronet, of the Guise baronets