John Donoghue

• John Donoghue (neuroscientist), professor of neuroscience at Brown University; co-founder of Cyberkinetics
• John Donoghue (writer), British humorist
• John Donoghue (footballer), Scottish football player
• John Francis Donoghue, American Roman Catholic bishop
• John P. Donoghue, American politician
• John Talbott Donoghue, American artist
• John Donoghue (physicist), American theoretical physicist